Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27090412 | 1.00 | HRAS (0.47) | HRASGAPDHMEN1USP2POLB | |
| SCHEMBL27090398 | 0.81 | CYP1A2 (0.40) | MEN1USP2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL27091934 | 0.81 | CYP1A2 (0.40) | MEN1USP2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29611607 | 0.78 | ADORA1 (0.54) | ADORA3 | |
| SCHEMBL27090409 | 0.78 | ADORA1 (0.54) | ADORA3 | |
| SCHEMBL18572826 | 0.78 | MEN1 (0.50) | HRASGAPDHMEN1USP2POLB | |
| SCHEMBL20938335 | 0.78 | P2RX3 (0.55) | GAPDHMEN1USP2POLBKMT2A | |
| SCHEMBL29611627 | 0.78 | MEN1 (0.50) | HRASGAPDHMEN1USP2POLB | |
| SCHEMBL29612073 | 0.78 | MEN1 (0.50) | HRASGAPDHMEN1USP2POLB | |
| SCHEMBL24313565 | 0.76 | ADORA3 (0.43) | MEN1USP2KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229067-A1 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |