Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.55 |
| ▸ | ADK | P55263 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 4/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938425 | 0.90 | P2RX3 (0.54) | P2RX3P2RX4P2RX2ADKCA1 | |
| SCHEMBL29612073 | 0.89 | MEN1 (0.50) | P2RX3P2RX4P2RX2ADKCA1 | |
| SCHEMBL18572826 | 0.89 | MEN1 (0.50) | P2RX3P2RX4P2RX2ADKCA1 | |
| SCHEMBL29611627 | 0.89 | MEN1 (0.50) | P2RX3P2RX4P2RX2ADKCA1 | |
| SCHEMBL7110607 | 0.89 | P2RX3 (0.53) | P2RX3P2RX4P2RX2ADKCA1 | |
| SCHEMBL6099599 | 0.88 | P2RX3 (0.55) | P2RX3P2RX4P2RX2CA1CA2 | |
| SCHEMBL6099608 | 0.88 | P2RX3 (0.55) | P2RX3P2RX4P2RX2CA1CA2 | |
| SCHEMBL20938423 | 0.84 | P2RX3 (0.49) | P2RX3P2RX4P2RX2ADKCA1 | |
| SCHEMBL13169185 | 0.84 | P2RX3 (0.75) | P2RX3P2RX4P2RX2MEN1USP2 | |
| SCHEMBL9189337 | 0.84 | P2RX3 (0.75) | P2RX3P2RX4P2RX2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019076633-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2019-04-25 | — | — | WO | disclosed |