Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611180 | 0.85 | HPGD (0.46) | USP30DPP4GPR119SMN1; SMN2 | |
| SCHEMBL24558188 | 0.75 | USP30 (0.39) | USP30DPP4IDO1TDO2GPR119 | |
| SCHEMBL31107289 | 0.75 | USP30 (0.39) | USP30DPP4IDO1TDO2GPR119 | |
| SCHEMBL17224909 | 0.74 | USP30 (0.42) | USP30DPP4IDO1TDO2GPR119 | |
| SCHEMBL31401077 | 0.72 | USP30 (0.47) | USP30DPP4GPR119PIK3CD | |
| SCHEMBL31022332 | 0.71 | GPR119 (0.42) | USP30DPP4IDO1TDO2GPR119 | |
| SCHEMBL34471700 | 0.71 | GPR119 (0.42) | USP30DPP4IDO1TDO2GPR119 | |
| SCHEMBL31022118 | 0.71 | GPR119 (0.42) | USP30DPP4IDO1TDO2GPR119 | |
| SCHEMBL9999452 | 0.71 | GPR119 (0.50) | USP30DPP4GPR119SMN1; SMN2 | |
| SCHEMBL12847405 | 0.71 | GPR119 (0.50) | USP30IDO1TDO2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022051565-A1 | SUBSTITUTED 4-PIPERIDINYL-QUINAZOLINES, 4-PIPERIDINYL-PYRIMIDINE-2-AMINES, AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Ikena Oncology, Inc. (US) | 2022-03-10 | — | — | WO | disclosed |