Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24558188 | 1.00 | USP30 (0.39) | USP30GPR119FNTAFNTBCDK4 | |
| SCHEMBL24558073 | 0.86 | USP30 (0.43) | USP30GPR119IDO1TDO2DPP4 | |
| SCHEMBL29046811 | 0.86 | USP30 (0.43) | USP30GPR119IDO1TDO2DPP4 | |
| SCHEMBL28671300 | 0.85 | DPP4 (0.33) | CDK4CCND1CCND3CDK6DPP4 | |
| SCHEMBL28671298 | 0.85 | DPP4 (0.33) | CDK4CCND1CCND3CDK6DPP4 | |
| SCHEMBL31022332 | 0.83 | GPR119 (0.42) | USP30GPR119FNTAFNTBIDO1 | |
| SCHEMBL34471700 | 0.83 | GPR119 (0.42) | USP30GPR119FNTAFNTBIDO1 | |
| SCHEMBL31022118 | 0.83 | GPR119 (0.42) | USP30GPR119FNTAFNTBIDO1 | |
| SCHEMBL4412062 | 0.82 | USP30 (0.54) | USP30DPP4TRPV3SETD7 | |
| SCHEMBL31107254 | 0.81 | TRPV3 (0.36) | USP30GPR119CDK4CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-B | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2024-07-19 | — | — | CN | disclosed |