Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31022118 | 1.00 | GPR119 (0.42) | GPR119USP30DPP4IDO1TDO2 | |
| SCHEMBL34471700 | 1.00 | GPR119 (0.42) | GPR119USP30DPP4IDO1TDO2 | |
| SCHEMBL24763869 | 0.91 | GPR119 (0.40) | GPR119USP30IDO1TDO2FNTA | |
| SCHEMBL31729058 | 0.88 | CYP3A4 (0.43) | GPR119USP30CXCR3TRPV3 | |
| SCHEMBL30729623 | 0.87 | CXCR3 (0.50) | GPR119CXCR3 | |
| SCHEMBL31491286 | 0.87 | CXCR3 (0.50) | GPR119CXCR3 | |
| SCHEMBL26958997 | 0.87 | CXCR3 (0.50) | GPR119CXCR3 | |
| SCHEMBL14465886 | 0.87 | CXCR3 (0.50) | GPR119CXCR3 | |
| SCHEMBL24764604 | 0.87 | GPR119 (0.42) | GPR119USP30IDO1TDO2TRPV3 | |
| SCHEMBL16652727 | 0.86 | GPR119 (0.48) | GPR119IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459483-A | Fused tricyclic compounds, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-08-09 | — | — | CN | disclosed |