Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demoxepam SCHEMBL78342 | 1.00 | CNR1 (0.54) | CNR1NTSR1OPRK1PDE4DCYP1A2 | |
| SCHEMBL11632406 | 0.87 | CNR1 (0.41) | CNR1NTSR1OPRK1PDE4DCYP1A2 | |
| SCHEMBL11631409 | 0.87 | PSEN1 (0.44) | CNR1NTSR1OPRK1PDE4DCYP1A2 | |
| SCHEMBL6527541 | 0.86 | GABRA1 (0.55) | CNR1NTSR1OPRK1PDE4DCYP1A2 | |
| SCHEMBL32681120 | 0.86 | GABRA1 (0.55) | CNR1NTSR1OPRK1PDE4DCYP1A2 | |
| SCHEMBL2846056 | 0.84 | KMT2A (0.47) | CYP1A2KDM4EGABRA1GABRG2GABRB3 | |
| SCHEMBL11319239 | 0.84 | LMNA (0.57) | CNR1NTSR1OPRK1PDE4DGABRP | |
| SCHEMBL7306150 | 0.80 | CYP1A2 (0.42) | CNR1NTSR1OPRK1PDE4DCYP1A2 | |
| SCHEMBL7306143 | 0.80 | CYP1A2 (0.42) | CNR1NTSR1OPRK1PDE4DCYP1A2 | |
| Desipramine SCHEMBL7763271 | 0.79 | CYP3A4 (0.47) | CNR1NTSR1OPRK1PDE4DCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816913-B | Preparation method of oxazepam intermediate | 华中药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-113816913-B | Preparation method of oxazepam intermediate | 华中药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115215809-A | Preparation method of oxazepam key intermediate | 华中药业股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112500359-B | Preparation method of lorazepam intermediate | 华中药业股份有限公司 | 2022-06-03 | — | — | CN | disclosed |