Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32681120 | 0.88 | GABRA1 (0.55) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL6527541 | 0.88 | GABRA1 (0.55) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11399009 | 0.85 | GABRA1 (0.57) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| Demoxepam SCHEMBL29611580 | 0.84 | CNR1 (0.54) | LMNACHRM1GABRA1GABRA5GABRA3 | |
| Demoxepam SCHEMBL78342 | 0.84 | CNR1 (0.54) | LMNACHRM1GABRA1GABRA5GABRA3 | |
| SCHEMBL10675729 | 0.82 | SMN1; SMN2 (0.39) | LMNAGABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7310022 | 0.81 | LMNA (0.43) | LMNACHRM1CCNE2CCNE1CDK2 | |
| SCHEMBL7310020 | 0.81 | LMNA (0.43) | LMNACHRM1CCNE2CCNE1CDK2 | |
| SCHEMBL7551382 | 0.78 | NSD2 (0.40) | LMNA | |
| SCHEMBL11632406 | 0.77 | CNR1 (0.41) | LMNAGABRA1GABRA5GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261987-A | ANTICONVULSANTS | GEROT PHARMAZEUTIKA GESELLSCHAFT M.B.H. (AT) | 1981-04-14 | — | — | US | disclosed |