Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142976 | 1.00 | LMNA (0.50) | LMNAKMT2AEPHX2ALDH1A1KDM4E | |
| SCHEMBL10712606 | 0.83 | ALDH1A1 (0.63) | LMNAKMT2AEPHX2ALDH1A1KDM4E | |
| SCHEMBL34472041 | 0.82 | L3MBTL1 (0.47) | LMNAKMT2AEPHX2ALDH1A1KDM4E | |
| SCHEMBL29838495 | 0.82 | L3MBTL1 (0.50) | KMT2AALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5464387 | 0.82 | L3MBTL1 (0.50) | KMT2AALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL30521352 | 0.80 | L3MBTL1 (0.53) | LMNAKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28130105 | 0.80 | LMNA (0.55) | LMNAKMT2AEPHX2ALDH1A1KDM4E | |
| SCHEMBL17856110 | 0.80 | L3MBTL1 (0.53) | LMNAKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15215634 | 0.79 | ALDH1A1 (0.47) | LMNAKMT2AEPHX2ALDH1A1KDM4E | |
| SCHEMBL20560664 | 0.79 | EPHX2 (0.51) | LMNAKMT2AEPHX2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805281-B | KRAS G12C inhibitors | 伊莱利利公司 | 2022-05-10 | — | — | CN | disclosed |