Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAP2 | P11137 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144926 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30310610 | 0.83 | MAP2 (0.60) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL697252 | 0.79 | MAPT (0.59) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29897041 | 0.78 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30366683 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL62193 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2399274 | 0.78 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL87871 | 0.78 | KDM4E (0.65) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2490053 | 0.78 | EIF4A3 (0.65) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2813085 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380732-B | Preparation method of fluoroindole carboxylic acid compound | 上海毕得医药科技股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-114380732-A | Preparation method of fluoro-indole carboxylic acid compounds | 上海毕得医药科技股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-114380732-B | Preparation method of fluoroindole carboxylic acid compound | 上海毕得医药科技股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-114380732-B | Preparation method of fluoroindole carboxylic acid compound | 上海毕得医药科技股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-114380732-B | Preparation method of fluoroindole carboxylic acid compound | 上海毕得医药科技股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-114380732-A | Preparation method of fluoro-indole carboxylic acid compounds | 上海毕得医药科技股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114380732-A | Preparation method of fluoro-indole carboxylic acid compounds | 上海毕得医药科技股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114380732-A | Preparation method of fluoro-indole carboxylic acid compounds | 上海毕得医药科技股份有限公司 | 2022-04-22 | — | — | CN | disclosed |