SCHEMBL2399274

SCHEMBL2399274

Cc1c(C(=O)O)[nH]c2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.63
HSD17B10 Q99714 4/20 0.63
KDM4E B2RXH2 5/20 0.62
HPGD P15428 4/20 0.62
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
MAPT P10636 2/20 0.58
HTT P42858 2/20 0.58
USP2 O75604 1/20 0.58
POLB P06746 2/20 0.57
FOLH1 Q04609 1/20 0.56
AHR P35869 1/20 0.55
DAO P14920 1/20 0.55
DDO Q99489 1/20 0.55
GFER P55789 2/20 0.54
GAA P10253 1/20 0.54
MAOA P21397 1/20 0.54
PKM P14618 1/20 0.53
NPY1R P25929 1/20 0.53
NPY2R P49146 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29897041 1.00 ALDH1A1 (0.63) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL30000925 0.89 ALDH1A1 (0.56) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL5273233 0.89 ALDH1A1 (0.56) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL2722021 0.88 ALDH1A1 (0.63) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL10704376 0.86 ALDH1A1 (0.61) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL8343752 0.85 ALDH1A1 (0.56) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL4493831 0.85 MAP2 (0.60) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL7338590 0.82 ALDH1A1 (0.56) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL5508274 0.82 ALDH1A1 (0.65) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL30595729 0.82 ALDH1A1 (0.56) ALDH1A1HSD17B10KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114704306-A Method for treating leakage water in construction of underground excavation tunnel 北京市市政四建设工程有限责任公司 2022-07-05 CN claimed
EP-2167077-A2 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR Bayer Schering Pharma Aktiengesellschaft (DE) 2010-03-31 EP claimed
US-20090023741-A1 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AG (DE) 2009-01-22 US claimed
WO-2008152099-A2 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-12-18 WO claimed
WO-2000006525-A9 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS HARVARD COLLEGE (US) 2000-04-20 WO claimed
EP-0990047-A2 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES Rapigene, Inc. (US) 2000-04-05 EP claimed
WO-2000006525-A2 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-02-10 WO claimed
WO-1999005319-A9 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE INC (US) 1999-06-17 WO claimed
WO-1999005319-A2 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE, INC. (US) 1999-02-04 WO claimed
WO-1995011895-A1 N-BENZOYL-4-OXY/THIO-2-SUBSTITUTED PIPERIDINES AS SUBSTANCE-P RECEPTOR ANTAGONISTS CIBA-GEIGY AG (CH) 1995-05-04 WO claimed
WO-2026107377-A1 PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL KARANICOLAS JOHN (US) 2026-05-21 WO disclosed
US-20260071243-A1 BIOLOGICAL PRODUCTION OF TRYPTOPHAN-DERIVED PRODUCTS UNIV TEXAS (US) 2026-03-12 US disclosed
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
US-20240383856-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-21 US disclosed
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-14 US disclosed
US-4794101-A MIXTURE OF PHTHALIDE DYE, FLUORAN COMPOUND AND POLYVALENT METAL SALT OF AN AROMATIC CARBOXYLIC ACID KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-12-27 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed
US-4731353-A METAL SALT OF INDOLE-2-CARBOXYLIC ACID COLOR DEVELOPER KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) 1988-03-15 US disclosed
EP-0249885-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-12-23 EP disclosed
EP-0234540-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383856-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 ALDH1A1 1825/4885HSD17B10 1094/4885KDM4E 967/4885
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 ALDH1A1 1825/4885HSD17B10 1094/4885KDM4E 967/4885
US-20090023741-A1 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR PTGER2, PTGER1, PTGDR2 ALDH1A1 834/4885HSD17B10 297/4885KDM4E 3048/4885
US-20260071243-A1 BIOLOGICAL PRODUCTION OF TRYPTOPHAN-DERIVED PRODUCTS TPH1, TPH2, SLC6A4 ALDH1A1 565/4885HSD17B10 572/4885KDM4E 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.