Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | SIK1 | P57059 | 2/20 | 0.40 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.40 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7726925 | 1.00 | HCAR3 (0.58) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL19836338 | 0.86 | GLP1R (0.53) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL29612495 | 0.86 | GLP1R (0.53) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL18009914 | 0.82 | HCAR3 (0.40) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL11396992 | 0.80 | RAB9A (0.61) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL29037722 | 0.79 | HCAR3 (0.38) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7721135 | 0.79 | HCAR3 (0.58) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL20665086 | 0.79 | HCAR3 (0.58) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL12730480 | 0.79 | HCAR3 (0.62) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL30914208 | 0.79 | HCAR3 (0.58) | HCAR3RAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |