Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 10/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18424750 | 1.00 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL19270712 | 0.94 | REN (0.38) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL19252786 | 0.89 | LMNA (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29613229 | 0.89 | LMNA (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18425287 | 0.84 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DSMPD1 | |
| SCHEMBL19252780 | 0.82 | PDE4A (0.36) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL19252791 | 0.82 | PDE4A (0.40) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL29613164 | 0.82 | PDE4A (0.40) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL19252795 | 0.80 | PDE4A (0.36) | PDE4BPDE4APDE4CPDE4DREN | |
| SCHEMBL18423334 | 0.80 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831942-B | Fused indazolopyridinone compounds as antiviral agents | 诺华股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109071447-B | Tetracyclic pyridinone compounds as antiviral agents | 诺华股份有限公司 | 2022-04-22 | — | — | CN | disclosed |