Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252786 | 1.00 | LMNA (0.33) | LMNAMAPK1HTTPPARGPPARA | |
| SCHEMBL19272914 | 0.90 | PPARG (0.31) | LMNAMAPK1HTTPPARGPPARA | |
| SCHEMBL29613166 | 0.89 | PDE4B (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18424750 | 0.89 | PDE4B (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19270712 | 0.83 | REN (0.38) | — | |
| SCHEMBL29613292 | 0.81 | CYP2C9 (0.36) | MAPK1PPARGPPARAHTR2AHTR2C | |
| SCHEMBL19252796 | 0.81 | CYP2C9 (0.36) | MAPK1PPARGPPARAHTR2AHTR2C | |
| SCHEMBL18424748 | 0.79 | LMNA (0.34) | LMNAMAPK1HTTPPARGPPARA | |
| SCHEMBL18425287 | 0.73 | PDE4B (0.48) | LMNAMAPK1HTTKDM4EALDH1A1 | |
| SCHEMBL19252777 | 0.72 | HTR2C (0.39) | MAPK1PPARGPPARAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071447-B | Tetracyclic pyridinone compounds as antiviral agents | 诺华股份有限公司 | 2022-04-22 | — | — | CN | disclosed |