Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182208 | 0.96 | MAPT (0.37) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL29613249 | 0.96 | MAPT (0.37) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL5615321 | 0.85 | SMN1; SMN2 (0.43) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL4146942 | 0.85 | MAPT (0.37) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL7131287 | 0.84 | KDM4E (0.40) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL5264237 | 0.83 | CYP1A2 (0.41) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL5615531 | 0.83 | ALDH1A1 (0.43) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL3918033 | 0.81 | MAPT (0.38) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL2398864 | 0.80 | MAPT (0.34) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL2400659 | 0.80 | KDM4E (0.38) | HTTSMN1; SMN2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613475-B1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES INC (US) | 1998-01-07 | — | — | EP | claimed |
| US-5699182-A | NAPHTHOPYRAN PHOTOCHROME AND HINDERED AMINOETHER LIGHT STABILIZER | XYTRONYX, INC. (US) | 1997-12-16 | — | — | US | claimed |
| WO-1996037576-A9 | LIGHT FATIGUE RESISTANT PHOTOCHROMIC FORMULATIONS | — | 1997-01-23 | — | — | WO | claimed |
| WO-1996037576-A1 | LIGHT FATIGUE RESISTANT PHOTOCHROMIC FORMULATIONS | XYTRONYX, INC. (US) | 1996-11-28 | — | — | WO | claimed |
| WO-1993010112-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1993-05-27 | — | — | WO | claimed |
| US-5066818-A | Lenses, plastic transparencies | PPG INDUSTRIES, INC. (US) | 1991-11-19 | — | — | US | claimed |
| US-8262945-B2 | Stabilization of photochromic systems | BASF SE (DE) | 2012-09-11 | — | — | US | disclosed |
| US-20090289236-A1 | STABILIZATION OF PHOTOCHROMIC SYSTEMS | DESTRO MARA | 2009-11-26 | — | — | US | disclosed |
| US-20070064195-A1 | Stabilization of photochromic systems | CIBA CORPORATION | 2007-03-22 | — | — | US | disclosed |
| EP-1709114-A1 | STABILIZATION OF PHOTOCHROMIC SYSTEMS | Ciba SC Holding AG (CH) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005030856-A1 | STABILIZATION OF PHOTOCHROMIC SYSTEMS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-04-07 | — | — | WO | disclosed |
| EP-0628064-B2 | PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-0728315-B1 | PHOTOCHROMIC COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE | PPG IND OHIO INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0628064-A1 | PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1994-12-14 | — | — | EP | disclosed |
| EP-0613475-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1994-09-07 | — | — | EP | disclosed |
| WO-1994008260-A1 | PHOTOCHROMIC COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE | PPG INDUSTRIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| WO-1993017071-A1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1993-09-02 | — | — | WO | disclosed |
| US-5238981-A | PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1993-08-24 | — | — | US | disclosed |
| WO-1993010112-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1993-05-27 | — | — | WO | disclosed |
| US-5066818-A | Lenses, plastic transparencies | PPG INDUSTRIES, INC. (US) | 1991-11-19 | — | — | US | disclosed |