Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287733 | 0.84 | S1PR1 (0.38) | PTGS2HTR2CS1PR1S1PR5GABRA1 | |
| SCHEMBL930219 | 0.84 | HTR2C (0.46) | PTGS2HTR2CCXCR5 | |
| SCHEMBL11277724 | 0.84 | HTR2C (0.46) | PTGS2HTR2CCXCR5 | |
| SCHEMBL11868492 | 0.82 | HTR2C (0.47) | PTGS2HTR2CCXCR5 | |
| SCHEMBL2969965 | 0.80 | PTGS2 (0.40) | PTGS2BCHEACHECHRNB2CHRNA4 | |
| SCHEMBL4476579 | 0.79 | CHRNB2 (0.57) | PTGS2BCHEACHECHRNB2CHRNA4 | |
| SCHEMBL28816105 | 0.79 | CHRNB2 (0.57) | PTGS2BCHEACHECHRNB2CHRNA4 | |
| Phosphine SCHEMBL2085260 | 0.78 | CHRNB2 (0.59) | PTGS2BCHEACHECHRNB2CHRNA4 | |
| SCHEMBL8130416 | 0.78 | HTR2C (0.64) | PTGS2HTR2CS1PR1S1PR5ACHE | |
| SCHEMBL1128179 | 0.78 | HTR2C (0.64) | PTGS2HTR2CS1PR1S1PR5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831942-B | Fused indazolopyridinone compounds as antiviral agents | 诺华股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109071447-B | Tetracyclic pyridinone compounds as antiviral agents | 诺华股份有限公司 | 2022-04-22 | — | — | CN | disclosed |