Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851115 | 0.87 | HTR2C (0.34) | S1PR1S1PR5PTGS2HTR2CCXCR5 | |
| SCHEMBL29613262 | 0.84 | PTGS2 (0.43) | S1PR1S1PR5PTGS2HTR2CCXCR5 | |
| SCHEMBL28000625 | 0.82 | ABCB1 (0.42) | PTGS2ABCB1HTR1AHTR7 | |
| SCHEMBL5379529 | 0.82 | PTPN1 (0.35) | PTGS2PTPRCPTPRFPTPN1CDC25B | |
| SCHEMBL788140 | 0.82 | CAMKK2 (0.35) | PTGS2PSMB5PTPRCPTPRFPTPN1 | |
| SCHEMBL68108 | 0.80 | PTGS2 (0.39) | PTGS2PSMB5 | |
| SCHEMBL28152698 | 0.78 | PTGS2 (0.39) | PTGS2ABCB1 | |
| SCHEMBL28153847 | 0.77 | PSMB5 (0.34) | PTGS2PSMB5ABCB1 | |
| SCHEMBL28152695 | 0.76 | ABCB1 (0.43) | PTGS2ABCB1HTR1AHTR7 | |
| SCHEMBL11277724 | 0.76 | HTR2C (0.46) | PTGS2HTR2CCXCR5ABCB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427468-B1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PLC (GB) | 2017-06-14 | — | — | EP | claimed |
| US-8772520-B2 | Preparation of a metal complex | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2014-07-08 | — | — | US | claimed |
| US-20120116109-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-05-10 | — | — | US | claimed |
| EP-2427468-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128316-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2010-11-11 | — | — | WO | claimed |
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| EP-3643694-B1 | METHOD FOR PRODUCING BUTADIENE COMPOUND | DAIKIN IND LTD (JP) | 2023-11-15 | — | — | EP | disclosed |
| EP-3643694-A1 | METHOD FOR PRODUCING BUTADIENE COMPOUND | Daikin Industries, Ltd. (JP) | 2020-04-29 | — | — | EP | disclosed |
| EP-2427468-B1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PLC (GB) | 2017-06-14 | — | — | EP | disclosed |
| US-8772520-B2 | Preparation of a metal complex | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2014-07-08 | — | — | US | disclosed |
| US-20120116109-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-05-10 | — | — | US | disclosed |
| EP-2427468-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-03-14 | — | — | EP | disclosed |
| CN-102190581-A | Process for preparing 4'-halogenalkyl-biphenyl-2-carboxylic acids | SALTIGO GMBH | 2011-09-21 | — | — | CN | disclosed |
| US-7867581-B2 | Retardation film and liquid crystal display device using the same | NIPPON OIL CORPORATION (JP) | 2011-01-11 | — | — | US | disclosed |
| WO-2010128316-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2010-11-11 | — | — | WO | disclosed |
| US-20090156770-A1 | Retardation film and liquid crystal display device using the same | NIPPON OIL CORPORATION (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-2060937-A1 | RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | Nippon Oil Corporation (JP) | 2009-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | ERG28, CYP51A1, MANBA | S1PR1 2128/4885S1PR5 3052/4885PTGS2 3458/4885 |
| US-20120116109-A1 | PREPARATION OF A METAL COMPLEX | PDCD1LG2, CD274, PDCD2L | S1PR1 3202/4885S1PR5 3338/4885PTGS2 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.