Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | C1R | P00736 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28732805 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAOAMAOBTDO2ADORA2A | |
| SCHEMBL29613286 | 0.86 | KDM4E (0.53) | ALDH1A1MAOAMAOBTDO2LMNA | |
| SCHEMBL5682766 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAOAMAOBADORA2ALMNA | |
| SCHEMBL29746285 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAOAMAOBADORA2ALMNA | |
| Hydrochloric Acid SCHEMBL38654589 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAOAMAOBLMNAKDM4E | |
| SCHEMBL6856561 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAOAMAOBLMNAKDM4E | |
| SCHEMBL27592710 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAOAMAOBLMNAKDM4E | |
| SCHEMBL10304851 | 0.80 | MEN1 (0.51) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL13169313 | 0.80 | AR (0.52) | ALDH1A1MAOAADORA2AKDM4EPTPN1 | |
| SCHEMBL29268752 | 0.77 | ALDH1A1 (0.55) | ALDH1A1ADORA2ALMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466913-B | Dihydro quinoline photochromic compounds | 光学转变有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-114466913-A | Dihydroquinoline photochromic compounds | 光学转变有限公司 | 2022-05-10 | — | — | CN | disclosed |