Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036825 | 0.89 | MAOA (0.58) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28732805 | 0.86 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29613264 | 0.86 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL15578480 | 0.79 | KDM4E (0.72) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL12732472 | 0.76 | KDM4E (0.56) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29746285 | 0.75 | ALDH1A1 (0.59) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5682766 | 0.75 | ALDH1A1 (0.59) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL14500756 | 0.74 | NCF1 (0.51) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4773101 | 0.74 | HSP90AA1 (0.51) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL17144673 | 0.74 | CYP1A1 (0.56) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466913-B | Dihydro quinoline photochromic compounds | 光学转变有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-114466913-A | Dihydroquinoline photochromic compounds | 光学转变有限公司 | 2022-05-10 | — | — | CN | disclosed |