Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | C1R | P00736 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27592710 | 1.00 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29746285 | 0.98 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5682766 | 0.98 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL38654589 | 0.97 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL27666421 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7444887 | 0.82 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL2036825 | 0.81 | MAOA (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL28732805 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RAB9AKDM4EMAOA | |
| SCHEMBL29613264 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RAB9AKDM4EMAOA | |
| SCHEMBL20172584 | 0.81 | RAB9A (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835469-B2 | Phosphorescent compounds and devices comprising the same | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2004-12-28 | — | — | US | disclosed |