Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | EIF4E | P06730 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227679 | 0.86 | PTGS2 (0.58) | ALDH1A1TDP1HTR7NPC1RAB9A | |
| SCHEMBL3335019 | 0.86 | ALDH1A1 (0.69) | ALDH1A1TDP1HTR7NPC1RAB9A | |
| SCHEMBL28233631 | 0.85 | HTR7 (0.52) | ALDH1A1TDP1HTR7NPC1RAB9A | |
| SCHEMBL27744304 | 0.84 | NPC1 (0.46) | ALDH1A1TDP1HTR7NPC1RAB9A | |
| SCHEMBL3489869 | 0.84 | HTR7 (0.51) | ALDH1A1TDP1HTR7NPC1RAB9A | |
| SCHEMBL2336139 | 0.83 | HTR7 (0.56) | ALDH1A1TDP1HTR7NPC1RAB9A | |
| SCHEMBL2957169 | 0.82 | NPC1 (0.70) | ALDH1A1TDP1NPC1RAB9AKMT2A | |
| SCHEMBL30785680 | 0.82 | NPC1 (0.70) | ALDH1A1TDP1NPC1RAB9AKMT2A | |
| SCHEMBL7773844 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1HTR7NPC1RAB9A | |
| SCHEMBL29676476 | 0.81 | APP (0.57) | ALDH1A1TDP1HTR7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229154-A | Preparation method of bifenazate intermediate | 帕潘纳(北京)科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-112047871-B | Preparation method of indole compound | 南京大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-112047871-A | Preparation method of indole compound | 南京大学 | 2020-12-08 | — | — | CN | disclosed |
| US-20190082845-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | INCURON INC (US) | 2019-03-21 | — | — | US | disclosed |
| CN-106967046-A | Preparation method of N-heteroaryl hydroxycarbazole compound | 浙江工业大学 | 2017-07-21 | — | — | CN | disclosed |
| CN-106957301-A | A kind of preparation method of the hydroxycarbazole class compound of N heteroaryls 2 | 浙江工业大学 | 2017-07-18 | — | — | CN | disclosed |
| US-20170165229-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | INCURON, INC. | 2017-06-15 | — | — | US | disclosed |
| US-20170165229-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | INCURON, INC. | 2017-06-15 | — | — | US | disclosed |
| US-9566265-B2 | Carbazole compounds and therapeutic uses of the compounds | INCURON, LLC (US) | 2017-02-14 | — | — | US | disclosed |
| US-9566265-B2 | Carbazole compounds and therapeutic uses of the compounds | INCURON, LLC (US) | 2017-02-14 | — | — | US | disclosed |
| US-6362380-B1 | REACTING 2-NITROCHLOROBENZENE AND A BORONIC ACID ; PALLADIUM CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| EP-0888261-B1 | PROCESS FOR PREPARING NITROBIPHENYLENE | BASF AG (DE) | 2001-11-28 | — | — | EP | disclosed |
| EP-0888261-A1 | PROCESS FOR PREPARING NITROBIPHENYLENE | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | EP | disclosed |
| US-5677328-A | SLEEP DISORDERS; PSYCHOLOGICAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1997033846-A1 | PROCESS FOR PREPARING NITROBIPHENYLENE | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-18 | — | — | WO | disclosed |
| EP-0771791-A1 | Ethylamino carbazole melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0536151-B1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | BOOTS CO PLC (GB) | 1994-09-14 | — | — | EP | disclosed |
| US-5302720-A | Biphenyl-substituted guanidine derivatives useful as hypoglycaemic agents | THE BOOTS COMPANY (GB) | 1994-04-12 | — | — | US | disclosed |
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992000273-A1 | ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | THE BOOTS COMPANY PLC (GB) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170165229-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | MALT1, PAICS, BCL9 | ALDH1A1 633/4885TDP1 1323/4885HTR7 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.