Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19307170 | 1.00 | IMPDH2 (0.54) | IMPDH2MAPTCDK5CDK5R1TAAR1 | |
| SCHEMBL19316703 | 0.86 | IMPDH2 (0.43) | IMPDH2MAPTGSK3BF10NPC1 | |
| SCHEMBL29614770 | 0.86 | IMPDH2 (0.55) | IMPDH2MAPK1AURKBPRMT3 | |
| SCHEMBL19307230 | 0.86 | IMPDH2 (0.55) | IMPDH2MAPK1AURKBPRMT3 | |
| SCHEMBL19307218 | 0.86 | RAB9A (0.47) | IMPDH2MAPTGSK3BNPC1RAB9A | |
| SCHEMBL29614745 | 0.86 | RAB9A (0.47) | IMPDH2MAPTGSK3BNPC1RAB9A | |
| SCHEMBL19307193 | 0.85 | NAMPT (0.44) | IMPDH2GSK3BF10NPC1RAB9A | |
| SCHEMBL19307104 | 0.85 | IMPDH2 (0.42) | IMPDH2MAPTGSK3BNPC1RAB9A | |
| SCHEMBL29614871 | 0.85 | IMPDH2 (0.42) | IMPDH2MAPTGSK3BNPC1RAB9A | |
| SCHEMBL19307111 | 0.84 | KDM4E (0.53) | IMPDH2MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | CORNELL UNIVERSITY | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | PTGES, PTGS1, PTGES2 | IMPDH2 551/4885MAPT 4843/4885CDK5 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.