Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577824 | 1.00 | NR3C1 (0.41) | NR3C1KDM1AKDM4ENPSR1HPGDS | |
| SCHEMBL29615607 | 0.84 | NR3C1 (0.51) | NR3C1KDM1AHPGDSMAOBPGR | |
| SCHEMBL20577702 | 0.84 | NR3C1 (0.51) | NR3C1KDM1AHPGDSMAOBPGR | |
| SCHEMBL18223690 | 0.82 | KDM1A (0.58) | KDM1AALDH1A1TSHRSMN1; SMN2PTGDR2 | |
| SCHEMBL20577865 | 0.77 | SCN9A (0.39) | KDM1AKDM4ENPSR1ALDH1A1TSHR | |
| SCHEMBL29615348 | 0.77 | SCN9A (0.39) | KDM1AKDM4ENPSR1ALDH1A1TSHR | |
| SCHEMBL18002768 | 0.74 | GRM5 (0.59) | KDM1AKDM4ENPSR1GRM5SMN1; SMN2 | |
| SCHEMBL2707348 | 0.73 | LRRK2 (0.43) | NR3C1KDM4EHPGDSPGRKIF11 | |
| SCHEMBL18223968 | 0.71 | CYP1A2 (0.48) | KDM4ENPSR1GRM5MAOBTRPV1 | |
| SCHEMBL10460598 | 0.70 | CYP1A2 (0.40) | KDM4EALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602807-B | Heterocyclic sulfonamide derivatives and drugs containing the same | EA制药株式会社 | 2022-05-13 | — | — | CN | disclosed |