Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615607 | 1.00 | NR3C1 (0.51) | NR3C1KIF11PGRKDM1AMAOB | |
| SCHEMBL20577824 | 0.84 | NR3C1 (0.41) | NR3C1KIF11PGRKDM1AMAOB | |
| SCHEMBL29615396 | 0.84 | NR3C1 (0.41) | NR3C1KIF11PGRKDM1AMAOB | |
| SCHEMBL16894230 | 0.79 | KDM1A (0.56) | KIF11PGRKDM1APTGDR2 | |
| SCHEMBL2004916 | 0.78 | RORC (0.46) | NR3C1PGRKDM1AHPGDSRORC | |
| SCHEMBL20577700 | 0.77 | KIF11 (0.45) | KIF11PGRCYP11B2 | |
| SCHEMBL29615293 | 0.77 | KIF11 (0.45) | KIF11PGRCYP11B2 | |
| SCHEMBL2458921 | 0.76 | PTGS2 (0.45) | MAOBPTGDR2PTGS2ALOX5APFEN1 | |
| SCHEMBL2707348 | 0.75 | LRRK2 (0.43) | NR3C1KIF11PGRHPGDSLRRK2 | |
| SCHEMBL16554418 | 0.75 | MAP4K4 (0.52) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602807-B | Heterocyclic sulfonamide derivatives and drugs containing the same | EA制药株式会社 | 2022-05-13 | — | — | CN | disclosed |
| EP-3412664-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | EA PHARMA CO LTD (JP) | 2022-03-30 | — | — | EP | disclosed |
| US-10584116-B2 | Heterocyclic sulfonamide derivative and medicine containing same | EA PHARMA CO., LTD. (JP) | 2020-03-10 | — | — | US | disclosed |
| US-20190023699-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | EA PHARMA CO., LTD. (JP) | 2019-01-24 | — | — | US | disclosed |
| EP-3412664-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | EA Pharma Co., Ltd. (JP) | 2018-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023699-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | TRPA1, TRPV1, TRPV2 | NR3C1 1669/4885KIF11 4552/4885PGR 3133/4885 |
| US-10584116-B2 | Heterocyclic sulfonamide derivative and medicine containing same | TRPA1, TRPV1, TRPV2 | NR3C1 1669/4885KIF11 4552/4885PGR 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.