Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577865 | 1.00 | SCN9A (0.39) | SCN9AALOX5APFEN1PIK3CAKDM4E | |
| SCHEMBL20577700 | 0.85 | KIF11 (0.45) | PIK3CAKDM4ENPSR1AAK1ALDH1A1 | |
| SCHEMBL29615293 | 0.85 | KIF11 (0.45) | PIK3CAKDM4ENPSR1AAK1ALDH1A1 | |
| SCHEMBL10460598 | 0.82 | CYP1A2 (0.40) | KDM4EACACBMEN1ALDH1A1KMT2A | |
| SCHEMBL29615396 | 0.77 | NR3C1 (0.41) | KDM4ENPSR1ALDH1A1KIF11KDM1A | |
| SCHEMBL20577824 | 0.77 | NR3C1 (0.41) | KDM4ENPSR1ALDH1A1KIF11KDM1A | |
| SCHEMBL18002768 | 0.74 | GRM5 (0.59) | KDM4ENPSR1KIF11KDM1ASMN1; SMN2 | |
| SCHEMBL3480516 | 0.73 | CYP11B2 (0.60) | ALOX5APFEN1 | |
| SCHEMBL18223968 | 0.71 | CYP1A2 (0.48) | SCN9APIK3CAKDM4ENPSR1ALDH1A1 | |
| SCHEMBL16663959 | 0.71 | GAA (0.38) | PIK3CAKDM4EAAK1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602807-B | Heterocyclic sulfonamide derivatives and drugs containing the same | EA制药株式会社 | 2022-05-13 | — | — | CN | disclosed |