Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919010 | 1.00 | NOS3 (0.49) | NOS3NOS1NOS2LNPEPHRH3 | |
| SCHEMBL14637040 | 0.85 | NOS3 (0.55) | NOS3NOS1NOS2LNPEPROCK1 | |
| SCHEMBL31619927 | 0.85 | NOS3 (0.55) | NOS3NOS1NOS2LNPEPROCK1 | |
| SCHEMBL7874082 | 0.83 | LRRK2 (0.48) | LNPEPHRH3LRRK2MAOAMAOB | |
| SCHEMBL31403631 | 0.82 | NOS3 (0.52) | NOS3NOS1NOS2LNPEPROCK1 | |
| SCHEMBL12234578 | 0.82 | HRH3 (0.47) | LNPEPHRH3LRRK2MAOAMAOB | |
| SCHEMBL20557326 | 0.81 | NOS3 (0.41) | NOS3NOS1NOS2LNPEPHRH3 | |
| SCHEMBL20445905 | 0.80 | LNPEP (0.46) | NOS3NOS1NOS2LNPEPROCK1 | |
| SCHEMBL21311492 | 0.80 | LOX (0.46) | LNPEPHRH3LRRK2SMN1; SMN2DYRK1A | |
| SCHEMBL22918946 | 0.79 | MAOA (0.47) | NOS3NOS1NOS2HRH3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003992-A1 | 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL) -PYRIMIDINE DERIVATIVES | Merck Patent GmbH (DE) | 2022-06-01 | — | — | EP | disclosed |
| CN-114174293-A | 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2022-03-11 | — | — | CN | disclosed |