Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437007 | 0.95 | HPGD (0.61) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| SCHEMBL229498 | 0.95 | HPGD (0.61) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| SCHEMBL566636 | 0.95 | HPGD (0.61) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| SCHEMBL1300333 | 0.95 | HPGD (0.61) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| Hydrochloric Acid SCHEMBL3885955 | 0.93 | HPGD (0.59) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| Hydrochloric Acid SCHEMBL7528728 | 0.93 | HPGD (0.59) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| Hydrochloric Acid SCHEMBL7526056 | 0.93 | HPGD (0.59) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| SCHEMBL5608372 | 0.84 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| SCHEMBL3568567 | 0.82 | HPGD (0.63) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 | |
| SCHEMBL1567597 | 0.80 | HPGD (0.61) | HPGDALDH1A1SMN1; SMN2HTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602807-B | Heterocyclic sulfonamide derivatives and drugs containing the same | EA制药株式会社 | 2022-05-13 | — | — | CN | disclosed |