Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.61 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.61 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.61 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.48 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.48 |
| ▸ | TFEB | P19484 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961596 | 1.00 | PTGER4 (0.61) | PTGER4PTGER3PTGER2PTGER1HTT | |
| SCHEMBL11683166 | 0.90 | PTGER4 (0.59) | PTGER4PTGER3PTGER2PTGER1HTT | |
| SCHEMBL11683167 | 0.90 | PTGER4 (0.59) | PTGER4PTGER3PTGER2PTGER1HTT | |
| SCHEMBL8161667 | 0.87 | MAPT (0.65) | PTGER4PTGER3PTGER2PTGER1SMN1; SMN2 | |
| SCHEMBL8161669 | 0.87 | MAPT (0.65) | PTGER4PTGER3PTGER2PTGER1SMN1; SMN2 | |
| SCHEMBL755995 | 0.87 | PTGER3 (0.59) | PTGER4PTGER3PTGER2PTGER1HTT | |
| SCHEMBL5147040 | 0.85 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1HTT | |
| SCHEMBL4278586 | 0.83 | ALDH1A1 (0.48) | PTGER4PTGER3PTGER2PTGER1KDM4E | |
| SCHEMBL4278583 | 0.83 | ALDH1A1 (0.48) | PTGER4PTGER3PTGER2PTGER1KDM4E | |
| SCHEMBL1536281 | 0.83 | PTGER1 (0.66) | PTGER4PTGER3PTGER2PTGER1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SHUNICHI SHIOZAWA (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SP1, AP1G1, JUN | PTGER4 3176/4885PTGER3 3194/4885PTGER2 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.