SCHEMBL755995

SCHEMBL755995

CC(C)CCCOc1ccccc1/C=C/C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 3/20 0.59
PTGER4 P35408 2/20 0.59
PTGER2 P43116 2/20 0.59
PTGER1 P34995 1/20 0.59
HTT P42858 2/20 0.55
KDM4E B2RXH2 2/20 0.52
GAA P10253 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
NFKB1 P19838 2/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
PPIA P62937 1/20 0.49
NFE2L2 Q16236 2/20 0.48
TFEB P19484 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
LMNA P02545 3/20 0.46
MAPT P10636 3/20 0.46
PLA2G1B P04054 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961596 0.87 PTGER4 (0.61) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL2961597 0.87 PTGER4 (0.61) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL5078092 0.85 PTGER1 (0.62) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL9716888 0.85 PTGER1 (0.62) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL5178116 0.84 PTGER1 (0.61) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL1356220 0.83 PTGER1 (0.64) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL14843147 0.83 PTGER1 (0.64) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL11685411 0.83 PTGER4 (0.64) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL4331860 0.82 PTGER1 (0.59) PTGER3PTGER4PTGER2PTGER1HTT
SCHEMBL4331862 0.82 PTGER1 (0.59) PTGER3PTGER4PTGER2PTGER1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3154510-B1 COMPOSITION FOR PROTECTING KERATIN MATERIALS FROM SUN OREAL (FR) 2022-01-19 EP claimed
EP-3107526-B1 TOPICAL ANHYDROUS FILL FORMULATION FOR ULTRAVIOLET FILTERS SCHERER TECHNOLOGIES LLC R P (US) 2020-07-29 EP claimed
EP-2853255-B1 Method of formulating a personal care product with substantially no whitening effect when applied on wet skin and compositions thereof HallStar Beauty and Personal Care Innovations Company (US) 2018-11-28 EP claimed
EP-3056192-B1 Complete anhydrous sunscreen composition with under water technology FREZYDERM S A (GR) 2018-11-21 EP claimed
EP-3195849-A1 UV BLOCKING FUNCTIONAL COMPOSITE POWDER PREPARED BY DOUBLY COATING INORGANIC POWDER WITH INORGANIC UV BLOCKING AGENT AND ORGANIC UV ABSORBER, AND UV BLOCKING COSMETIC COMPOSITION USING SAME Chemland. Co., Ltd. (KR) 2017-07-26 EP claimed
EP-1594454-B1 FILM FORMING HYDROALCOHOLIC FOAM STIEFEL RES AUSTRALIA PTY LTD (AU) 2016-07-27 EP claimed
US-9211237-B2 Film foaming hydroalcoholic foam STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2015-12-15 US claimed
US-20140017176-A1 FILM FOAMING HYDROALCOHOLIC FOAM STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2014-01-16 US claimed
EP-1782792-B1 Ultraviolet ray absorbing composite powder IWASE COSFA CO LTD (JP) 2013-01-09 EP claimed
EP-1360146-B1 PROCESS FOR THE PREPARATION OF AQUEOUS SUSPENSIONS OF ANIONIC COLLOIDAL SILICA HAVING A NEUTRAL PH AND APPLICATIONS THEREOF AZ ELECTRONIC MATERIALS USA (US) 2012-06-13 EP claimed
EP-1899015-B1 COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT DSM IP ASSETS BV (NL) 2012-03-21 EP claimed
US-20060233727-A9 Film foaming hydroalcoholic foam CONNETICS AUSTRALIA PTY LTD. (AU) 2006-10-19 US claimed
US-20060067894-A1 Film foaming hydroalcoholic foam CONNETICS AUSTRALIA PTY LTD. (AU) 2006-03-30 US claimed
EP-1594454-A1 FILM FORMING HYDROALCOHOLIC FOAM Connetics Australia Pty Limited (AU) 2005-11-16 EP claimed
EP-1059911-B1 FORMULATIONS WITH AN ANTI-VIRAL EFFECT MERCK PATENT GMBH (DE) 2005-04-20 EP claimed
WO-2004071479-A1 FILM FOAMING HYDROALCOHOLIC FOAM CONNETICS AUSTRALIA PTY LTD (AU) 2004-08-26 WO claimed
EP-1059911-A1 FORMULATIONS WITH AN ANTI-VIRAL EFFECT MERCK PATENT GmbH (DE) 2000-12-20 EP claimed
WO-1999044578-A1 FORMULATIONS WITH AN ANTI-VIRAL EFFECT MERCK PATENT GMBH (DE) 1999-09-10 WO claimed
EP-0509904-B1 Microencapsulation of sunscreen products, their preparation process, cosmetic and pharmaceutical compositions containing said microcapsules and their applications ROUSSEL UCLAF (FR) 1996-02-28 EP claimed
EP-4037636-A1 ANTI-UV COSMETIC COMPOSITION Coatex (FR) 2022-08-10 EP disclosed
WO-2021064299-A1 ANTI-UV COSMETIC COMPOSITION COATEX (FR) 2021-04-08 WO disclosed
EP-2775997-B1 COSMETIC AND DERMATOLOGICAL PHOTOPROTECTIVE PREPARATION WITH IMPROVED WATER RESISTANCE BEIERSDORF AG (DE) 2019-08-07 EP disclosed
US-20190038538-A1 RNA COMPLEXES THAT INHIBIT MELANIN PRODUCTION OLIX PHARMACEUTICALS, INC. (KR) 2019-02-07 US disclosed
US-10064801-B2 RNA complexes that inhibit melanin production OLIX PHARMACEUTICALS, INC. (KR) 2018-09-04 US disclosed
EP-2210619-B1 Scar covering with UV protection BEIERSDORF AG (DE) 2017-12-20 EP disclosed
EP-3195849-A1 UV BLOCKING FUNCTIONAL COMPOSITE POWDER PREPARED BY DOUBLY COATING INORGANIC POWDER WITH INORGANIC UV BLOCKING AGENT AND ORGANIC UV ABSORBER, AND UV BLOCKING COSMETIC COMPOSITION USING SAME Chemland. Co., Ltd. (KR) 2017-07-26 EP disclosed
WO-2017017523-A1 RNA COMPLEXES THAT INHIBIT MELANIN PRODUCTION OLIX PHARMACEUTICALS, INC. (KR) 2017-02-02 WO disclosed
US-20170027837-A1 RNA COMPLEXES THAT INHIBIT MELANIN PRODUCTION OLIX PHARMACEUTICALS, INC. (KR) 2017-02-02 US disclosed
EP-1594454-B1 FILM FORMING HYDROALCOHOLIC FOAM STIEFEL RES AUSTRALIA PTY LTD (AU) 2016-07-27 EP disclosed
US-9265726-B2 Foamable suspension gel STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2016-02-23 US disclosed
WO-2016005689-A1 USE OF AN AMINATED HOMOPOLYMER FOR ENCAPSULATING INGREDIENTS, METHOD OF SYNTHESIZING AN AEMA HOMOPOLYMER AND METHOD OF ENCAPSULATING INGREDIENTS ISP INVESTMENTS INC. (US) 2016-01-14 WO disclosed
WO-2016005693-A1 STATISTICAL CATIONIC COPOLYMERS, METHOD FOR THEIR SYNTHESIS AND THEIR USE FOR INGREDIENT ENCAPSULATION ISP INVESTMENTS INC. (US) 2016-01-14 WO disclosed
US-9211237-B2 Film foaming hydroalcoholic foam STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2015-12-15 US disclosed
EP-2206494-B1 Foamable suspension gel STIEFEL RES AUSTRALIA PTY LTD (AU) 2015-12-02 EP disclosed
US-9012418-B2 Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) L'OREAL (FR) 2015-04-21 US disclosed
US-20140248220-A1 FOAMABLE SUSPENSION GEL STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2014-09-04 US disclosed
US-8758728-B2 Foamable suspension gel STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2014-06-24 US disclosed
EP-2688650-A1 FILM-FORMING COMPOSITION CONTAINING A SUN FILTER, AND USE THEREOF FOR THE TREATMENT OF SCARS Laboratoires Urgo (FR) 2014-01-29 EP disclosed
US-20140017176-A1 FILM FOAMING HYDROALCOHOLIC FOAM STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2014-01-16 US disclosed
US-20130280309-A1 FOAMABLE SUSPENSION GEL STIEFEL RESEARCH AUSTRALIA PTY LTD. (AU) 2013-10-24 US disclosed
US-8562959-B2 Film foaming hydroalcoholic foam STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2013-10-22 US disclosed
US-8475770-B2 Foamable suspension gel STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2013-07-02 US disclosed
EP-2209462-B1 Cosmetic product for protecting the skin from environmental influences COTY GERMANY GMBH (DE) 2013-04-10 EP disclosed
WO-2012131237-A1 FILM-FORMING COMPOSITION CONTAINING A SUN FILTER, AND USE THEREOF FOR THE TREATMENT OF SCARS LABORATOIRES URGO (FR) 2012-10-04 WO disclosed
US-8158109-B2 Foamable suspension gel STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2012-04-17 US disclosed
US-20110318278-A1 FOAMABLE SUSPENSION GEL STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2011-12-29 US disclosed
EP-2210619-A2 Scar covering with UV protection Beiersdorf AG (DE) 2010-07-28 EP disclosed
EP-2206494-A1 Foamable suspension gel Stiefel Research Australia Pty Ltd (AU) 2010-07-14 EP disclosed
EP-2181698-A2 Cosmetic formula with siloxane elastomers and particulate material Beiersdorf AG (DE) 2010-05-05 EP disclosed
EP-2181699-A1 Cosmetic formula with siloxane elastomers for improving microbiological stability Beiersdorf AG (DE) 2010-05-05 EP disclosed
EP-2179721-A1 Cosmetic formula with new siloxane elastomers Beiersdorf AG (DE) 2010-04-28 EP disclosed
US-20090117063-A1 Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) DURANTON ALBERT 2009-05-07 US disclosed
EP-2010133-A2 FOAMABLE SUSPENSION GEL Stiefel Research Australia Pty Ltd (AU) 2009-01-07 EP disclosed
EP-1748753-B1 BENZYLIDENEN-ßDICARBONYL COMPOUNDS AS NOVEL UV-ABSORBERS SYMRISE GMBH & CO KG (DE) 2008-10-01 EP disclosed
EP-1961453-A2 Benzyliden-ß-dicarbonyl compounds as UV-absorbers Symrise GmbH & Co. KG (DE) 2008-08-27 EP disclosed
WO-2008007224-A2 FOAMABLE SUSPENSION GEL STIEFEL RESEARCH AUSTRALIA PTY LTD (US) 2008-01-17 WO disclosed
US-20070237724-A1 Foamable suspension gel STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) 2007-10-11 US disclosed
EP-1778175-A1 ALPHA-BENZOYL-CINNAMIC ACID NITRILE AS NOVEL UV-ABSORBERS Symrise GmbH & Co. KG (DE) 2007-05-02 EP disclosed
EP-1748753-A1 BENZYLIDENEN-ßDICARBONYL COMPOUNDS AS NOVEL UV-ABSORBERS Symrise GmbH & Co. KG (DE) 2007-02-07 EP disclosed
US-20060233727-A9 Film foaming hydroalcoholic foam CONNETICS AUSTRALIA PTY LTD. (AU) 2006-10-19 US disclosed
EP-1642560-A1 Sunscreen and skincare compositions containing DNA-repairing enzymes STADA ARZNEIMITTEL AG (DE) 2006-04-05 EP disclosed
US-20060067894-A1 Film foaming hydroalcoholic foam CONNETICS AUSTRALIA PTY LTD. (AU) 2006-03-30 US disclosed
WO-2006015954-A1 ALPHA-BENZOYL-CINNAMIC ACID NITRILE AS NOVEL UV-ABSORBERS SYMRISE GMBH & CO. KG (DE) 2006-02-16 WO disclosed
WO-2005107692-A1 BENZYLIDENE-β-DICARBONYL COMPOUNDS AS NOVEL UV-ABSORBERS SYMRISE GMBH & CO. KG (DE) 2005-11-17 WO disclosed
EP-1594454-A1 FILM FORMING HYDROALCOHOLIC FOAM Connetics Australia Pty Limited (AU) 2005-11-16 EP disclosed
US-20050222071-A1 Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) L'OREAL (FR) 2005-10-06 US disclosed
EP-1059911-B1 FORMULATIONS WITH AN ANTI-VIRAL EFFECT MERCK PATENT GMBH (DE) 2005-04-20 EP disclosed
EP-1466892-A1 Novel indanylidene compounds Symrise GmbH & Co. KG (DE) 2004-10-13 EP disclosed
WO-2004071479-A1 FILM FOAMING HYDROALCOHOLIC FOAM CONNETICS AUSTRALIA PTY LTD (AU) 2004-08-26 WO disclosed
EP-1341752-B1 NOVEL INDANYLIDENE COMPOUNDS SYMRISE GMBH & CO KG (DE) 2004-08-04 EP disclosed
US-20040057917-A1 Pharmaceutical composition for treatment and /or prevention of a light-dermatosis HANS-DIETER PRENTNER (AT) 2004-03-25 US disclosed
WO-2003092643-A1 LIGHT-PROTECTION FORMULATIONS USING ACRYLONITRILE DERIVATIVES SYMRISE GMBH & CO. KG (DE) 2003-11-13 WO disclosed
EP-1341752-A1 NOVEL INDANYLIDENE COMPOUNDS HAARMANN & REIMER GMBH (DE) 2003-09-10 EP disclosed
WO-2002038537-A1 NOVEL INDANYLIDENE COMPOUNDS HAARMANN & REIMER GMBH (DE) 2002-05-16 WO disclosed
EP-1153600-A2 Sunscreen and skincare compositions containing DNA-repairing enzymes STADA ARZNEIMITTEL AG (DE) 2001-11-14 EP disclosed
US-6265180-B1 STERILE NONTOXIC DISPERSION FOR USE IN TRANSFERRING MATERIALS INTO CELLS MIBELLE AG COSMETICS (CH) 2001-07-24 US disclosed
US-6265180-B1 STERILE NONTOXIC DISPERSION FOR USE IN TRANSFERRING MATERIALS INTO CELLS MIBELLE AG COSMETICS (CH) 2001-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222071-A1 Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) DCLRE1B, POLRMT, ADAR PTGER3 4810/4885PTGER4 4713/4885PTGER2 4814/4885
US-20090117063-A1 Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) DCLRE1B, POLRMT, ADAR PTGER3 4810/4885PTGER4 4713/4885PTGER2 4814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.