Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 7/20 | 1.00 |
| ▸ | TPO | P07202 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CBX7 | O95931 | 1/20 | 0.37 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14936647 | 1.00 | MPO (1.00) | MPOTPOGAAMAPK1RXFP1 | |
| Pf-06282999 SCHEMBL14940947 | 0.94 | MPO (0.90) | MPOTPOGAAMAPK1RXFP1 | |
| SCHEMBL14937052 | 0.91 | MPO (1.00) | MPOTPOGAAMAPK1RXFP1 | |
| SCHEMBL14936542 | 0.90 | MPO (0.81) | MPOTPOGAAMAPK1RXFP1 | |
| SCHEMBL14947169 | 0.90 | MPO (0.81) | MPOTPOGAAMAPK1RXFP1 | |
| SCHEMBL14936736 | 0.89 | MPO (0.80) | MPOTPOGAAMAPK1GRIN1 | |
| SCHEMBL14937082 | 0.88 | MPO (0.78) | MPOTPOGAAMAPK1RXFP1 | |
| Pf-06282999 SCHEMBL14936135 | 0.88 | MPO (1.00) | MPOTPOGAAMAPK1SLC9A1 | |
| SCHEMBL14936166 | 0.86 | MPO (0.76) | MPOTPOGAAMAPK1GRIN1 | |
| SCHEMBL14937124 | 0.86 | MPO (0.76) | MPOTPOGAAMAPK1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383158-B2 | Detection of high-risk unstable atherosclerotic plaque | THE HEART RESEARCH INSTITUTE LTD (AU) | 2025-08-12 | — | — | US | claimed |
| US-20240138701-A1 | DETECTION OF HIGH-RISK UNSTABLE ATHEROSCLEROTIC PLAQUE | THE HEART RESEARCH INSTITUTE LTD (AU) | 2024-05-02 | — | — | US | claimed |
| CN-116236486-B | Use of myeloperoxidase inhibitors in the preparation of cardioprotective agents | 复旦大学附属中山医院 | 2024-03-22 | — | — | CN | claimed |
| WO-2024031149-A1 | METHODS FOR THE DETECTION OF MYELOPEROXIDASE | THE UNIVERSITY OF SYDNEY (AU) | 2024-02-15 | — | — | WO | claimed |
| CN-116236486-A | Use of myeloperoxidase inhibitors in the preparation of cardioprotective agents | 复旦大学附属中山医院 | 2023-06-09 | — | — | CN | claimed |
| US-12570606-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| WO-2025227119-A1 | MYELOPEROXIDASE FLUORESCENCE IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2025-10-30 | — | — | WO | disclosed |
| US-12383158-B2 | Detection of high-risk unstable atherosclerotic plaque | THE HEART RESEARCH INSTITUTE LTD (AU) | 2025-08-12 | — | — | US | disclosed |
| US-20250182844-A1 | Methods for Identifying Shared Biological Pathways Between Diseases Using Mendelian Randomization | AMPEL BIOSOLUTIONS, LLC | 2025-06-05 | — | — | US | disclosed |
| US-20250090729-A1 | Methods and Products to Detect, Minimize and Treat TRAP-Related Tissue Reactions and Tissue Injury Associated With Medical Devices | Cell and Molecular Tissue Engineering, LLC (US) | 2025-03-20 | — | — | US | disclosed |
| EP-4519878-A2 | METHODS FOR IDENTIFYING SHARED BIOLOGICAL PATHWAYS BETWEEN DISEASES USING MENDELIAN RANDOMIZATION | Ampel Biosolutions, LLC (US) | 2025-03-12 | — | — | EP | disclosed |
| EP-4465936-A1 | METHODS AND PRODUCTS TO DETECT, MINIMIZE AND TREAT TRAP-RELATED TISSUE REACTIONS AND TISSUE INJURY ASSOCIATED WITH MEDICAL DEVICES | Cell And Molecular Tissue Engineering, LLC (US) | 2024-11-27 | — | — | EP | disclosed |
| WO-2024031149-A1 | METHODS FOR THE DETECTION OF MYELOPEROXIDASE | THE UNIVERSITY OF SYDNEY (AU) | 2024-02-15 | — | — | WO | disclosed |
| WO-2023215618-A2 | METHODS FOR IDENTIFYING SHARED BIOLOGICAL PATHWAYS BETWEEN DISEASES USING MENDELIAN RANDOMIZATION | AMPEL BIOSOLUTIONS, LLC (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023141237-A1 | METHODS AND PRODUCTS TO DETECT, MINIMIZE AND TREAT TRAP-RELATED TISSUE REACTIONS AND TISSUE INJURY ASSOCIATED WITH MEDICAL DEVICES | Cell and Molecular Tissue Engineering, LLC (US) | 2023-07-27 | — | — | WO | disclosed |
| CN-116236486-A | Use of myeloperoxidase inhibitors in the preparation of cardioprotective agents | 复旦大学附属中山医院 | 2023-06-09 | — | — | CN | disclosed |
| CN-116236486-A | Use of myeloperoxidase inhibitors in the preparation of cardioprotective agents | 复旦大学附属中山医院 | 2023-06-09 | — | — | CN | disclosed |
| CN-110177581-B | Myeloperoxidase imaging agents | 通用医疗公司 | 2023-01-03 | — | — | CN | disclosed |
| US-20220340524-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2022-10-27 | — | — | US | disclosed |
| US-11352326-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220340524-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | MPO 1/4885TPO 11/4885GAA 129/4885 |
| US-12570606-B2 | Myeloperoxidase imaging agents | MPO, CBR1, NOX1 | MPO 1/4885TPO 143/4885GAA 1743/4885 |
| US-11352326-B2 | Myeloperoxidase imaging agents | MPO, CAT, EPX | MPO 1/4885TPO 15/4885GAA 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.