Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23149005 | 0.90 | ESRRG (0.36) | ESRRGTSHRKDM1ASSTR1SSTR4 | |
| Trifluoroacetic Acid SCHEMBL29068369 | 0.84 | ESRRG (0.39) | ESRRGPPARALMNACYP2C9TSHR | |
| Trifluoroacetic Acid SCHEMBL29878366 | 0.83 | KDM1A (0.51) | ESRRGKDM1A | |
| SCHEMBL25323656 | 0.79 | EPHX1 (0.36) | ESRRGLMNATSHRMEN1CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL21382138 | 0.79 | P2RY14 (0.42) | ESRRGCYP2C9CYP3A4KDM1AP2RY14 | |
| Trifluoroacetic Acid SCHEMBL30945174 | 0.79 | P2RY14 (0.44) | CYP2C9MEN1CYP3A4KMT2AKDM1A | |
| Trifluoroacetic Acid SCHEMBL23455778 | 0.78 | HTR3A (0.50) | KDM1A | |
| Trifluoroacetic Acid SCHEMBL21382110 | 0.77 | TSHR (0.40) | ESRRGTSHRKDM1AP2RY14 | |
| SCHEMBL23149093 | 0.77 | F2R (0.39) | PPARALMNACYP2C9TSHRBLM | |
| Trifluoroacetic Acid SCHEMBL21381816 | 0.77 | CACNA1G (0.41) | ESRRGP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401968-A | Novel heterocyclic monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2022-04-26 | — | — | CN | disclosed |