Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15151146 | 0.83 | MAOA (0.51) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| Trifluoroacetic Acid SCHEMBL29616606 | 0.83 | ESRRG (0.41) | KDM1AESRRG | |
| Trifluoroacetic Acid SCHEMBL21382110 | 0.82 | TSHR (0.40) | KDM1AESRRG | |
| Trifluoroacetic Acid SCHEMBL21381816 | 0.81 | CACNA1G (0.41) | ESRRG | |
| Trifluoroacetic Acid SCHEMBL29068369 | 0.81 | ESRRG (0.39) | KDM1AESRRG | |
| Trifluoroacetic Acid SCHEMBL23091869 | 0.81 | KDM1A (0.48) | KDM1ACHRNB2CHRNA7CHRNA4ESRRG | |
| Trifluoroacetic Acid SCHEMBL10006604 | 0.80 | CHRNA7 (0.47) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| Trifluoroacetic Acid SCHEMBL30945174 | 0.80 | P2RY14 (0.44) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL10006673 | 0.80 | P2RY14 (0.54) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL23455778 | 0.80 | HTR3A (0.50) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790112-B | Cyanopyrrolidine derivatives having activity as USP30 inhibitors | 特殊治疗有限公司 | 2022-08-26 | — | — | CN | disclosed |