SCHEMBL29616642

SCHEMBL29616642

NCCCC[C@H](N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MME P08473 5/20 0.57
ACE P12821 4/20 0.57
CPA1 P15085 2/20 0.57
ACE2 Q9BYF1 2/20 0.57
CA2 P00918 1/20 0.52
MC4R P32245 2/20 0.51
MC5R P33032 2/20 0.51
MC3R P41968 2/20 0.51
ITGB3 P05106 3/20 0.50
ITGA2B P08514 3/20 0.50
MMP2 P08253 1/20 0.50
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30643724 0.91 ERAP2 (0.55) MMEACECPA1ACE2CA2
SCHEMBL30973666 0.91 ERAP2 (0.55) MMEACECPA1ACE2CA2
SCHEMBL31167405 0.90 MME (0.50) MMEACECPA1ACE2MC4R
SCHEMBL31253365 0.89 ERAP2 (0.53) MMEACECPA1ACE2MC4R
SCHEMBL31026925 0.89 MME (0.65) MMEACECPA1ACE2CA2
SCHEMBL12464463 0.87 FCER2 (0.52) FCER2
SCHEMBL31264142 0.87 MME (0.66) MMEACECPA1ACE2CA2
SCHEMBL29494074 0.87 MME (0.66) MMEACECPA1ACE2CA2
SCHEMBL1374146 0.87 MMP2 (0.64) MMEACECPA1ACE2ITGB3
SCHEMBL1374145 0.87 MMP2 (0.64) MMEACECPA1ACE2ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612343-B2 PSMA binder and use thereof Shiya Pharmaceutical, Inc (CN) 2026-04-28 US disclosed
US-20250360236-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2025-11-27 US disclosed
EP-4525935-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS Deutsches Krebsforschungszentrum (DE) 2025-03-26 EP disclosed
CN-119156234-A Prostate Specific Membrane Antigen (PSMA) ligands 德国癌症研究中心公共法律基金会 2024-12-17 CN disclosed
WO-2023222679-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2023-11-23 WO disclosed
WO-2023222682-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2023-11-23 WO disclosed
US-11638765-B2 Double-labeled probe for molecular imaging and use thereof DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2023-05-02 US disclosed
US-20220315507-A1 PSMA BINDER AND USE THEREOF SHANGHAI FO ZE MEDICAL TECHNOLOGY CO., LTD (CN) 2022-10-06 US disclosed
EP-4011903-A1 PSMA COMBINER AND USE THEREOF Shanghai Fo Ze Medical Technology Co., Ltd. (CN) 2022-06-15 EP disclosed
US-20220118121-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS WITH IMPROVED TISSUE SPECIFICITY DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360236-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS KLK3, FOLH1, MPI MME 381/4885ACE 2427/4885CPA1 303/4885
US-20220315507-A1 PSMA BINDER AND USE THEREOF KLK3, FOLH1, SHBG MME 431/4885ACE 3174/4885CPA1 774/4885
US-12612343-B2 PSMA binder and use thereof KLK3, AR, PSMA1 MME 981/4885ACE 1449/4885CPA1 48/4885
US-11638765-B2 Double-labeled probe for molecular imaging and use thereof ANXA1, ANXA5, CD47 MME 3220/4885ACE 4306/4885CPA1 983/4885
US-20220118121-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS WITH IMPROVED TISSUE SPECIFICITY FOLH1, ACP3, PSMA3 MME 859/4885ACE 3632/4885CPA1 278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.