SCHEMBL1374146

SCHEMBL1374146

NCCCC[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.64
MME P08473 3/20 0.56
ITGB3 P05106 2/20 0.54
ITGA2B P08514 2/20 0.54
ERAP2 Q6P179 1/20 0.53
LNPEP Q9UIQ6 1/20 0.53
LTA4H P09960 1/20 0.52
ACE P12821 2/20 0.51
CPA1 P15085 2/20 0.51
ACE2 Q9BYF1 2/20 0.51
GNPAT O15228 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17510189 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL3360183 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL30688845 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29531496 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL1374145 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
Hydrochloric Acid SCHEMBL11183447 0.99 MMP2 (0.63) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29531290 0.97 MMP2 (0.62) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29689355 0.97 MMP2 (0.62) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29376846 0.97 MMP2 (0.62) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29539550 0.97 MMP2 (0.62) MMP2MMEITGB3ITGA2BERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678240-A2 BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES Hangzhou Dac Biotech Co., Ltd. (CN) 2026-01-14 EP claimed
EP-3319936-B1 BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES HANGZHOU DAC BIOTECH CO LTD (CN) 2025-12-17 EP claimed
US-20250270247-A1 ANTIBODY DRUG CONJUGATES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-08-28 US claimed
US-12364767-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-07-22 US claimed
CN-119857156-A Antibody drug conjugates 武田药品工业株式会社 2025-04-22 CN claimed
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
CN-119770674-A Antibody drug conjugates 武田药品工业株式会社 2025-04-08 CN claimed
EP-4507734-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES Debiopharm Research & Manufacturing S.A. (CH) 2025-02-19 EP claimed
CN-119255824-A Ligand-drug conjugates with improved pharmacokinetic and drug release profiles 德比欧药物研究有限公司 2025-01-03 CN claimed
US-20250002530-A1 AROMATIC-CATIONIC PEPTIDES AND USES OF SAME STEALTH BIOTHERAPEUTICS INC. (US) 2025-01-02 US claimed
CN-114040779-A Conjugates of cell binding molecules containing branched linkers and cytotoxic agents 杭州多禧生物科技有限公司 2022-02-11 CN claimed
EP-3478121-A1 METHOD FOR SAMPLING GINGIVAL METABOLITES The Procter and Gamble Company (US) 2019-05-08 EP claimed
CN-109414109-A Method for sampling gums metabolin 宝洁公司 2019-03-01 CN claimed
US-9964472-B2 Methods for sampling gingival metabolites THE PROCTER & GAMBLE COMPANY (US) 2018-05-08 US claimed
US-20180003598-A1 METHODS FOR SAMPLING GINGIVAL METABOLITES THE PROCTER & GAMBLE COMPANY 2018-01-04 US claimed
WO-2018005335-A1 METHOD FOR SAMPLING GINGIVAL METABOLITES THE PROCTER & GAMBLE COMPANY (US) 2018-01-04 WO claimed
CN-107356756-A A kind of fluorescence probe and its synthetic method and the application in circulating tumor cell detection 广州医科大学附属第五医院 2017-11-17 CN claimed
CN-106456633-A Sugar metabolism improving agent 三得利控股株式会社 2017-02-22 CN claimed
CN-106455664-A Composition with high content of cyclic dipeptide 三得利控股株式会社 2017-02-22 CN claimed
EP-2185552-B1 DIPEPTOID PRODRUGS AND THE USE THEREOF BAYER IP GMBH (DE) 2014-03-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002530-A1 AROMATIC-CATIONIC PEPTIDES AND USES OF SAME ARG2, OAT, PDF MMP2 1296/4885MME 736/4885ITGB3 4531/4885
US-20250270247-A1 ANTIBODY DRUG CONJUGATES STING1, CGAS, TBK1 MMP2 4803/4885MME 3685/4885ITGB3 3509/4885
US-12364767-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM MMP2 1828/4885MME 2501/4885ITGB3 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.