Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 6/20 | 0.49 |
| ▸ | CALCR | P30988 | 6/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29380215 | 0.90 | RAMP3 (0.53) | RAMP3CALCRCXCR4 | |
| SCHEMBL30175378 | 0.89 | RAMP3 (0.56) | RAMP3CALCRCXCR4 | |
| SCHEMBL31188444 | 0.88 | NRP1 (0.48) | RAMP3CALCROPRM1OPRK1 | |
| SCHEMBL30261962 | 0.87 | RAMP3 (0.52) | RAMP3CALCR | |
| SCHEMBL5057725 | 0.86 | CXCR4 (0.45) | OPRM1OPRK1CXCR4 | |
| SCHEMBL29906304 | 0.86 | OPRM1 (0.47) | RAMP3CALCROPRM1OPRK1CXCR4 | |
| SCHEMBL29380657 | 0.85 | OPRM1 (0.53) | RAMP3CALCROPRM1OPRK1CXCR4 | |
| SCHEMBL29680195 | 0.85 | RAMP3 (0.52) | RAMP3CALCRCXCR4 | |
| SCHEMBL30974402 | 0.85 | NPY2R (0.55) | RAMP3CALCROPRM1OPRK1 | |
| SCHEMBL30988895 | 0.85 | RAMP3 (0.53) | RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367300-A1 | Nanomaterial and Methods of Use Thereof | UNIVERSITY OF CONNECTICUT (US) | 2025-12-04 | — | — | US | disclosed |
| US-20250302762-A1 | NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2025-10-02 | — | — | US | disclosed |
| US-20250302971-A1 | Therapeutic Nanomaterials | UNIV CONNECTICUT (US) | 2025-10-02 | — | — | US | disclosed |
| US-12214043-B2 | Therapeutic nanomaterials | UNIVERSITY OF CONNECTICUT | 2025-02-04 | — | — | US | disclosed |
| US-20220133893-A1 | Therapeutic Nanomaterials | UNIVERSITY OF CONNECTICUT | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250302971-A1 | Therapeutic Nanomaterials | TIE1, TEKT1, POLRMT | RAMP3 4232/4885CALCR 2464/4885OPRM1 4301/4885 |
| US-20220133893-A1 | Therapeutic Nanomaterials | TIE1, TEKT1, POLRMT | RAMP3 4232/4885CALCR 2464/4885OPRM1 4301/4885 |
| US-20250367300-A1 | Nanomaterial and Methods of Use Thereof | EPCAM, CD47, JAK2 | RAMP3 4144/4885CALCR 3553/4885OPRM1 2567/4885 |
| US-20250302762-A1 | NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF | JAK2, JAK1, CHMP4B | RAMP3 4437/4885CALCR 2879/4885OPRM1 1681/4885 |
| US-12214043-B2 | Therapeutic nanomaterials | TIE1, TEKT1, POLRMT | RAMP3 4232/4885CALCR 2464/4885OPRM1 4301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.