Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221458 | 1.00 | ALOX5 (0.50) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL11801543 | 1.00 | ALOX5 (0.50) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL94454 | 1.00 | ALOX5 (0.50) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL5268694 | 1.00 | ALOX5 (0.50) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL30564891 | 1.00 | ALOX5 (0.50) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL1021186 | 1.00 | ALOX5 (0.50) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| Ethane SCHEMBL28065381 | 0.98 | ALOX5 (0.49) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL1022048 | 0.98 | ALOX5 (0.49) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL549360 | 0.92 | HTT (0.47) | ALOX5PTGS2TYRCYP3A4MEN1 | |
| SCHEMBL30568741 | 0.92 | HTT (0.47) | ALOX5PTGS2TYRCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759780-B2 | Hindered amines | 3V SIGMA S.P.A. (IT) | 2020-09-01 | — | — | US | disclosed |
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2020-07-30 | — | — | US | disclosed |
| EP-3424977-B1 | HINDERED POLYMERIC AMINES | 3V SIGMA SPA (IT) | 2020-03-18 | — | — | EP | disclosed |
| EP-3428156-B1 | HINDERED AMINES | 3V SIGMA SPA (IT) | 2020-02-12 | — | — | EP | disclosed |
| US-20190016702-A1 | HINDERED AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-17 | — | — | US | disclosed |
| EP-3428156-A1 | HINDERED AMINES | 3V SIGMA S.p.A (IT) | 2019-01-16 | — | — | EP | disclosed |
| EP-3424977-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.p.A (IT) | 2019-01-09 | — | — | EP | disclosed |
| US-20190002631-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-03 | — | — | US | disclosed |
| US-9725578-B2 | Sterically hindered polymeric amines and their use as polymer stabilizers | 3V SIGMA S.P.A. (IT) | 2017-08-08 | — | — | US | disclosed |
| EP-2632914-B1 | NEW STERICALLY HINDERED POLYMERIC AMINES AND THEIR USE AS POLYMER STABILIZERS | 3V SIGMA SPA (IT) | 2015-12-16 | — | — | EP | disclosed |
| EP-2366732-A2 | Mixtures of sterically hindered amines for polymer stabilisation | 3V SIGMA S.p.A (IT) | 2011-09-21 | — | — | EP | disclosed |
| US-20110224336-A1 | MIXTURES OF STERICALLY HINDERED AMINES FOR POLYMER STABILIZATION | 3V SIGMA S.P.A. (IT) | 2011-09-15 | — | — | US | disclosed |
| US-8003718-B2 | Oligomeric sterically hindered amines and their use as polymer stabilisers | 3V SIGMA S.P.A. (IT) | 2011-08-23 | — | — | US | disclosed |
| US-20100204371-A1 | STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS | 3V SIGMA S.P.A. (IT) | 2010-08-12 | — | — | US | disclosed |
| EP-2216364-A1 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA S.p.A (IT) | 2010-08-11 | — | — | EP | disclosed |
| US-7713444-B2 | Mixtures of sterically hindered amines for the stabilisation of polymers | 3V SIGMA S.P.A. (IT) | 2010-05-11 | — | — | US | disclosed |
| US-20090270535-A1 | MIXTURES OF STERICALLY HINDERED AMINES FOR THE STABILISATION OF POLYMERS | 3V SIGMA S.P.A. (IT) | 2009-10-29 | — | — | US | disclosed |
| US-20090270536-A1 | OLIGOMERIC STERICALLY HINDERED AMINES AND THEIR USE AS POLYMER STABILISERS | 3V SIGMA S.P.A. (IT) | 2009-10-29 | — | — | US | disclosed |
| EP-2112198-A1 | Mixtures of sterically hindered amines for the stabilisation of polymers | 3V SIGMA S.p.A (IT) | 2009-10-28 | — | — | EP | disclosed |
| EP-2112141-A1 | Oligomeric sterically hindered amines and their use as polymer stabilizers | 3V SIGMA S.p.A (IT) | 2009-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | PARG, PARN, PUF60 | ALOX5 1740/4885PTGS2 2722/4885TYR 1776/4885 |
| US-20100204371-A1 | STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS | CBR3, SIGMAR1, NPSR1 | ALOX5 911/4885PTGS2 2329/4885TYR 3370/4885 |
| US-20090270536-A1 | OLIGOMERIC STERICALLY HINDERED AMINES AND THEIR USE AS POLYMER STABILISERS | PCBP1, PARG, PARN | ALOX5 768/4885PTGS2 1733/4885TYR 565/4885 |
| US-20190016702-A1 | HINDERED AMINES | PARG, TAAR5, PARN | ALOX5 519/4885PTGS2 2634/4885TYR 267/4885 |
| US-10759780-B2 | Hindered amines | PARG, TAAR5, PARN | ALOX5 519/4885PTGS2 2634/4885TYR 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.