Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087678 | 0.91 | CHRM2 (0.52) | S1PR5S1PR1GRK5CDK8FAAH | |
| SCHEMBL29087681 | 0.91 | CHRM2 (0.52) | S1PR5S1PR1GRK5CDK8FAAH | |
| SCHEMBL29617602 | 0.89 | S1PR5 (0.52) | S1PR5S1PR1GRK5CDK8PDGFRA | |
| SCHEMBL29087736 | 0.89 | CHRM2 (0.46) | S1PR5S1PR1GRK5CDK8FAAH | |
| SCHEMBL29087738 | 0.89 | CHRM2 (0.46) | S1PR5S1PR1GRK5CDK8FAAH | |
| SCHEMBL29617639 | 0.89 | CHRM2 (0.46) | S1PR5S1PR1GRK5CDK8FAAH | |
| SCHEMBL29087771 | 0.88 | L3MBTL1 (0.48) | S1PR5S1PR1GRK5CDK8PDGFRA | |
| SCHEMBL29087769 | 0.88 | L3MBTL1 (0.48) | S1PR5S1PR1GRK5CDK8PDGFRA | |
| SCHEMBL29617609 | 0.88 | ALDH1A1 (0.47) | S1PR5S1PR1GRK5CDK8PDGFRA | |
| SCHEMBL30646817 | 0.87 | S1PR5 (0.43) | S1PR5S1PR1GRK5CDK8FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247374-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | Telo Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |