Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.46 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617629 | 0.92 | CCR2 (0.46) | ALDH1A1FAAHDRD4KDM4ECACNA1G | |
| SCHEMBL30646811 | 0.92 | CCR2 (0.46) | ALDH1A1FAAHDRD4KDM4ECACNA1G | |
| SCHEMBL29087767 | 0.90 | S1PR5 (0.46) | ALDH1A1S1PR1S1PR5GRK5CDK8 | |
| SCHEMBL29617620 | 0.90 | KDM4E (0.43) | ALDH1A1FAAHOPRL1KDM4EGAA | |
| SCHEMBL29087755 | 0.90 | KDM4E (0.43) | ALDH1A1FAAHOPRL1KDM4EGAA | |
| SCHEMBL29617640 | 0.88 | S1PR5 (0.52) | ALDH1A1S1PR1S1PR5GRK5CDK8 | |
| SCHEMBL29617605 | 0.87 | CYP3A4 (0.41) | ALDH1A1PAX8KCNH2KDM4EGAA | |
| SCHEMBL29087730 | 0.87 | KDM4E (0.40) | ALDH1A1S1PR1S1PR5OPRL1JAK3 | |
| SCHEMBL29617612 | 0.86 | GPBAR1 (0.41) | ALDH1A1OPRL1KCNH2KDM4EGAA | |
| SCHEMBL30646810 | 0.86 | CHRM2 (0.41) | ALDH1A1FAAHOPRL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247374-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | Telo Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |