Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1085604 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| Methane SCHEMBL28322282 | 0.98 | ALDH1A1 (0.55) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL1284068 | 0.83 | MAPT (0.53) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL28109244 | 0.82 | MAPT (0.43) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL2219710 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL8568179 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2APOLB | |
| Ethylene SCHEMBL27749127 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3577339 | 0.76 | MAPT (0.52) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL319309 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL227454 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127231-A1 | PROCESS FOR THE PREPARTION OF AMIFAMPRIDINE PHOSPHATE | SHILPA MEDICARE LTD (IN) | 2022-04-28 | — | — | US | claimed |
| US-20240092779-A1 | USP1 INHIBITORS AND USES THEREOF | ZENTAUR THERAPEUTICS USA INC. | 2024-03-21 | — | — | US | disclosed |
| CN-117720533-A | MetTL3 inhibitor compound and pharmaceutical composition and application thereof | 北京华益健康药物研究中心 | 2024-03-19 | — | — | CN | disclosed |
| CN-117396473-A | Imidazopyridinyl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| US-20220127231-A1 | PROCESS FOR THE PREPARTION OF AMIFAMPRIDINE PHOSPHATE | SHILPA MEDICARE LTD (IN) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127231-A1 | PROCESS FOR THE PREPARTION OF AMIFAMPRIDINE PHOSPHATE | PMM2, TYMP, MVD | ALDH1A1 964/4885MAPT 3088/4885TDP1 1107/4885 |
| US-20240092779-A1 | USP1 INHIBITORS AND USES THEREOF | USP1, USP28, USP2 | ALDH1A1 788/4885MAPT 1272/4885TDP1 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.