SCHEMBL29618182

SCHEMBL29618182

O=[N+]([O-])c1ccc(-[n+]2ccc(-c3ccccc3)cc2)c([N+](=O)[O-])c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.64
NPC1 O15118 1/20 0.64
ATM Q13315 1/20 0.64
ALDH1A1 P00352 3/20 0.46
MAPK1 P28482 3/20 0.46
HIF1A Q16665 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CRHBP P24387 3/20 0.45
CRHR2 Q13324 3/20 0.45
TDP1 Q9NUW8 1/20 0.45
CES2 O00748 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
MITF O75030 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13648647 1.00 RAB9A (0.64) RAB9ANPC1ATMALDH1A1MAPK1
Hydrochloric Acid SCHEMBL8068701 0.98 NPC1 (0.67) RAB9ANPC1ATMALDH1A1MAPK1
SCHEMBL11694301 0.94 NPC1 (0.62) RAB9ANPC1ATMALDH1A1MAPK1
SCHEMBL12216699 0.93 NPC1 (0.60) RAB9ANPC1ATMALDH1A1MAPK1
Hydrochloric Acid SCHEMBL599994 0.92 NPC1 (0.65) RAB9ANPC1ATMALDH1A1MAPK1
Bromide SCHEMBL5144105 0.92 NPC1 (0.61) RAB9ANPC1ATMALDH1A1MAPK1
Hydrochloric Acid SCHEMBL30343291 0.92 NPC1 (0.65) RAB9ANPC1ATMALDH1A1MAPK1
SCHEMBL741714 0.87 NPC1 (0.62) RAB9ANPC1ATMALDH1A1MAPK1
SCHEMBL30109383 0.87 ALDH1A1 (0.54) RAB9ANPC1ATMALDH1A1MAPK1
SCHEMBL5156780 0.87 NPC1 (0.56) RAB9ANPC1ATMALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539136-B Molecular derivative for circular dichroism spectrum chiral recognition, preparation method and application 常州大学 2024-05-31 CN claimed
CN-114539136-A Molecular derivative for circular dichroism spectrum chiral recognition, preparation method and application 常州大学 2022-05-27 CN claimed
CN-114539136-B Molecular derivative for circular dichroism spectrum chiral recognition, preparation method and application 常州大学 2024-05-31 CN disclosed
CN-114539136-B Molecular derivative for circular dichroism spectrum chiral recognition, preparation method and application 常州大学 2024-05-31 CN disclosed
CN-114539136-A Molecular derivative for circular dichroism spectrum chiral recognition, preparation method and application 常州大学 2022-05-27 CN disclosed
CN-114539136-A Molecular derivative for circular dichroism spectrum chiral recognition, preparation method and application 常州大学 2022-05-27 CN disclosed