Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ESPL1 | Q14674 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30343291 | 1.00 | NPC1 (0.65) | NPC1RAB9AATMTDP1ALDH1A1 | |
| SCHEMBL11694301 | 0.98 | NPC1 (0.62) | NPC1RAB9AATMTDP1ALDH1A1 | |
| Bromide SCHEMBL5144105 | 0.97 | NPC1 (0.61) | NPC1RAB9AATMTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8068701 | 0.94 | NPC1 (0.67) | NPC1RAB9AATMTDP1ALDH1A1 | |
| SCHEMBL29595963 | 0.93 | NPC1 (0.58) | NPC1RAB9AATMTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11217818 | 0.93 | NPC1 (0.58) | NPC1RAB9AATMTDP1ALDH1A1 | |
| SCHEMBL10439894 | 0.93 | NPC1 (0.58) | NPC1RAB9AATMTDP1ALDH1A1 | |
| SCHEMBL29618182 | 0.92 | RAB9A (0.64) | NPC1RAB9AATMTDP1ALDH1A1 | |
| SCHEMBL13648647 | 0.92 | RAB9A (0.64) | NPC1RAB9AATMTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30611013 | 0.91 | NPC1 (0.56) | NPC1RAB9AATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257478-A1 | APPARATUS AND METHOD FOR PRODUCTION OF FORMATE FROM CARBON DIOXIDE | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2025-08-14 | — | — | US | claimed |
| US-20060033088-A1 | Polymer for a photochromic compound matrix, and a matrix comprising the said polymer | GYONGTAE KIM (KR) | 2006-02-16 | — | — | US | claimed |
| EP-1598408-A1 | A polymer for a photochromic compound matrix, and a matrix comprising the said polymer | Kim, Gyongtae (KR) | 2005-11-23 | — | — | EP | claimed |
| US-12447437-B2 | Carbon dioxide adsorption-desorption device | KABUSHIKI KAISHA TOSHIBA (JP) | 2025-10-21 | — | — | US | disclosed |
| US-20250257478-A1 | APPARATUS AND METHOD FOR PRODUCTION OF FORMATE FROM CARBON DIOXIDE | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2025-08-14 | — | — | US | disclosed |
| US-20230102938-A1 | CARBON DIOXIDE ADSORPTION-DESORPTION DEVICE | KABUSHIKI KAISHA TOSHIBA (JP) | 2023-03-30 | — | — | US | disclosed |
| EP-2905361-B1 | METHOD OF FORMING A METAL COATING | TOYOTA MOTOR CO LTD (JP) | 2022-01-05 | — | — | EP | disclosed |
| EP-2862936-B1 | OXIDOREDUCTASE REACTION CONTROL USING AMINO SUBSTITUTED BIPYRIDINIUM COMPOUNDS | AMANO ENZYME INC (JP) | 2021-12-22 | — | — | EP | disclosed |
| EP-2848667-B1 | Electrochromic single and two-core viologens and optical articles containing them | ESSILOR INT (FR) | 2019-04-10 | — | — | EP | disclosed |
| EP-3170789-B1 | PRODUCTION PROCESS FOR FLUOROSULFONYLIMIDE AMMONIUM SALT | NIPPON SODA CO (JP) | 2018-04-18 | — | — | EP | disclosed |
| US-9823534-B2 | Electrochromic single and two-core viologens and optical articles containing them | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2017-11-21 | — | — | US | disclosed |
| US-20060033088-A1 | Polymer for a photochromic compound matrix, and a matrix comprising the said polymer | GYONGTAE KIM (KR) | 2006-02-16 | — | — | US | disclosed |
| EP-1598408-A1 | A polymer for a photochromic compound matrix, and a matrix comprising the said polymer | Kim, Gyongtae (KR) | 2005-11-23 | — | — | EP | disclosed |
| EP-1477484-A1 | Oxonol dye compound, optical information recording medium using the same, and optical information | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6646132-B2 | Optical recording media | FUJI PHOTO FILM CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1253148-A2 | Oxonol dye compound, optical information recording medium using the same, and optical information | FUJI PHOTO FILM CO., LTD. (JP) | 2002-10-30 | — | — | EP | disclosed |
| US-20020009669-A1 | Information recording medium and novel oxonol compound | FUJIFILM CORPORATION (JP) | 2002-01-24 | — | — | US | disclosed |
| US-6225024-B1 | METHINE OXONOL DYE | FUJI PHOTO FILM CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |
| EP-0962923-A1 | Information recording medium and novel oxonol compound | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-4024150-A | Method of preparing an N,N'-bis(p-cyanophenyl)-4,4'-bipyridylium salt | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020009669-A1 | Information recording medium and novel oxonol compound | CACNA1S, KCNN1, KCNN2 | NPC1 3921/4885RAB9A 1805/4885ATM 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.