Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.52 |
| ▸ | CA2 | P00918 | 8/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664409 | 0.80 | CCNT1 (0.53) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618315 | 0.78 | CA1 (0.51) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29664713 | 0.76 | CA1 (0.50) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618358 | 0.76 | CA1 (0.47) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618349 | 0.74 | CA1 (0.51) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL2871965 | 0.73 | CA1 (0.72) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL30494258 | 0.73 | BCAT1 (0.57) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL10248292 | 0.73 | KMT2A (0.60) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618325 | 0.73 | KMT2A (0.71) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL24517810 | 0.73 | SCN10A (0.64) | SCN10ANR1I2CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591293-A | Fused ring compound as Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |