Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664409 | 0.82 | CCNT1 (0.53) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618325 | 0.76 | KMT2A (0.71) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618336 | 0.76 | CA1 (0.52) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618315 | 0.75 | CA1 (0.51) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618349 | 0.73 | CA1 (0.51) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL30494258 | 0.72 | BCAT1 (0.57) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29664713 | 0.72 | CA1 (0.50) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29618331 | 0.72 | MEN1 (0.52) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL10248292 | 0.72 | KMT2A (0.60) | CA1CA2POLBCASP6CTDSP1 | |
| SCHEMBL29664582 | 0.71 | P2RX4 (0.58) | CA1CA2POLBCASP6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591293-A | Fused ring compound as Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |