Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29618378 | 0.98 | KCNK3 (0.48) | KCNK3KCNK9SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29618385 | 0.83 | RAB9A (0.41) | KCNK3KCNK9SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29618368 | 0.76 | MEN1 (0.46) | SMN1; SMN2KDM4EMEN1KMT2ASCN10A | |
| SCHEMBL29618400 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL113971 | 0.75 | KCNK9 (0.66) | KCNK3KCNK9SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29618334 | 0.74 | PARP1 (0.57) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL29618331 | 0.74 | MEN1 (0.52) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL29618311 | 0.73 | SPR (0.45) | SMN1; SMN2KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL29923785 | 0.72 | HDAC4 (0.60) | KCNK3KCNK9KDM4ERPS6KA2HDAC4 | |
| SCHEMBL29664409 | 0.72 | CCNT1 (0.53) | MEN1KMT2AMAPTSCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591293-A | Fused ring compound as Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |