Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24517017 | 1.00 | PRKCI (0.34) | PRKCIDYRK1AGSK3BNPC1RAB9A | |
| SCHEMBL31344821 | 0.75 | MAPKAPK2 (0.41) | PRKCIDYRK1AGSK3BRAB9ACYP1A2 | |
| SCHEMBL4145121 | 0.73 | NPC1 (0.40) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL1669684 | 0.72 | DYRK1A (0.41) | PRKCIDYRK1ARAB9ADRD2DRD3 | |
| SCHEMBL29618321 | 0.72 | DYRK1A (0.41) | PRKCIDYRK1ARAB9ADRD2DRD3 | |
| SCHEMBL1506640 | 0.71 | KDM4E (0.42) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL29618318 | 0.71 | KDM4E (0.42) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL984492 | 0.71 | PRKCI (0.48) | PRKCIDYRK1ARAB9ADRD2DRD3 | |
| SCHEMBL9235864 | 0.69 | NPC1 (0.44) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL31540886 | 0.69 | PRKCI (0.47) | PRKCIDYRK1ARAB9ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591293-A | Fused ring compound as Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |