SCHEMBL29618976

SCHEMBL29618976

Fc1cccc2c(F)cccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
GPR84 Q9NQS5 1/20 0.41
ACHE P22303 1/20 0.40
HPRT1 P00492 1/20 0.40
TYMS P04818 1/20 0.38
NFE2L2 Q16236 3/20 0.38
PARP1 P09874 1/20 0.38
BCHE P06276 1/20 0.38
DAO P14920 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2A6 P11509 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
DDO Q99489 1/20 0.37
MPO P05164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5015496 1.00 CES2 (0.43) CES2CES1GPR84ACHEHPRT1
SCHEMBL12405315 0.93 HPRT1 (0.48) CES2CES1GPR84ACHEHPRT1
SCHEMBL6562728 0.85 HPRT1 (0.46) ACHEHPRT1NFE2L2DAOCYP1A2
SCHEMBL30366540 0.85 HPRT1 (0.46) ACHEHPRT1NFE2L2DAOCYP1A2
SCHEMBL20356016 0.83 CES2 (0.39) CES2CES1GPR84ACHEHPRT1
SCHEMBL15352162 0.83 CES2 (0.39) CES2CES1GPR84HPRT1TYMS
SCHEMBL4106168 0.83 PARP1 (0.43) CES2CES1GPR84TYMSPARP1
SCHEMBL15352423 0.83 CES2 (0.33) CES2CES1GPR84ACHEHPRT1
SCHEMBL1991031 0.83 ALDH1A1 (0.68) TYMSNFE2L2PARP1ALDH1A1CYP3A4
SCHEMBL7824137 0.83 CES2 (0.33) CES2CES1GPR84ACHEHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022107759-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION 日産化学株式会社 2022-05-27 WO disclosed