Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 6/20 | 0.39 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461316 | 0.87 | KIT (0.45) | GPR119KITSMARCA2SMARCA4PBRM1 | |
| SCHEMBL29619441 | 0.82 | SMARCA2 (0.53) | EGLN2ACACBEIF2AK4CYP11B2GPR119 | |
| SCHEMBL31505682 | 0.76 | HDAC2 (0.42) | ACACBCYP11B2GPR119NR1H2 | |
| SCHEMBL24461328 | 0.76 | KDM4E (0.40) | EHMT2STSMEN1KMT2A | |
| SCHEMBL29619389 | 0.76 | KDM4E (0.40) | EHMT2STSMEN1KMT2A | |
| SCHEMBL22470063 | 0.75 | KMT2A (0.43) | EGLN2OXTRAVPR1AEIF2AK4CYP11B2 | |
| SCHEMBL31293862 | 0.74 | OXTR (0.40) | EGLN2OXTRAVPR1AACACBEIF2AK4 | |
| SCHEMBL26683395 | 0.74 | OXTR (0.39) | EGLN2OXTRAVPR1AACACBEIF2AK4 | |
| SCHEMBL30666241 | 0.74 | OXTR (0.39) | EGLN2OXTRAVPR1AACACBEIF2AK4 | |
| SCHEMBL20898976 | 0.73 | GPR119 (0.46) | EGLN2OXTRAVPR1AACACBEIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109426-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |