Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619603 | 0.88 | MAPT (0.48) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL29619619 | 0.87 | ALDH1A1 (0.52) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL29619614 | 0.85 | MAPT (0.39) | MAPTLMNAKMT2AALDH1A1TP53 | |
| SCHEMBL24654265 | 0.84 | PTGDR2 (0.51) | ALDH1A1GABRA1GABRB2GABRG2GABRB3 | |
| SCHEMBL29619584 | 0.84 | PTGDR2 (0.51) | ALDH1A1GABRA1GABRB2GABRG2GABRB3 | |
| SCHEMBL29619626 | 0.80 | HTR6 (0.38) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL24654091 | 0.80 | HTR6 (0.38) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL29619636 | 0.80 | TP53 (0.55) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL15560244 | 0.72 | MAPT (0.48) | MAPTLMNAKMT2AALDH1A1GABRA1 | |
| SCHEMBL29891629 | 0.71 | PDE4A (0.51) | MAPTLMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082817-A1 | 3-THREE-MEMBERED SPIROOXINDOLE DERIVATIVE SYNTHESIZING METHOD | 苏州大学 | 2022-04-28 | — | — | WO | disclosed |