Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 6/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619626 | 1.00 | HTR6 (0.38) | HTR6MEN1KMT2APARK7MAPT | |
| SCHEMBL29619586 | 0.80 | MAPT (0.47) | MEN1KMT2AMAPTLMNAGABRA1 | |
| SCHEMBL29619584 | 0.69 | PTGDR2 (0.51) | GABRA1GABRB2BACE1BACE2CTSD | |
| SCHEMBL24654265 | 0.69 | PTGDR2 (0.51) | GABRA1GABRB2BACE1BACE2CTSD | |
| SCHEMBL29619603 | 0.68 | MAPT (0.48) | MEN1KMT2AMAPTLMNABACE1 | |
| SCHEMBL29619619 | 0.68 | ALDH1A1 (0.52) | MEN1KMT2AMAPTLMNABACE1 | |
| SCHEMBL28515905 | 0.67 | SLC27A2 (0.46) | HTR6MEN1KMT2AMAPTLMNA | |
| SCHEMBL29619573 | 0.67 | SLC27A2 (0.46) | HTR6MEN1KMT2AMAPTLMNA | |
| SCHEMBL29619574 | 0.67 | HCRTR1 (0.46) | HTR6MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29619636 | 0.66 | TP53 (0.55) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315533-A1 | METHOD FOR SYNTHESIZING 3-SPIRO THREE-MEMBERED RING INDOLINONE DERIVATIVE | SOOCHOW UNIVERSITY (CN) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315533-A1 | METHOD FOR SYNTHESIZING 3-SPIRO THREE-MEMBERED RING INDOLINONE DERIVATIVE | NES, NISCH, NCL | HTR6 793/4885MEN1 751/4885KMT2A 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.