Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23213252 | 1.00 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL23213368 | 0.78 | MRGPRX4 (0.38) | — | |
| SCHEMBL23213258 | 0.72 | ADRA2A (0.36) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL18894040 | 0.70 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL23434932 | 0.69 | LMNA (0.48) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL22206862 | 0.68 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL30446707 | 0.68 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL2355498 | 0.67 | ADRB2 (0.31) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL24775387 | 0.67 | PDE2A (0.47) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL23295193 | 0.66 | MRGPRX4 (0.41) | MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390705-A | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-114555606-B | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114555606-A | 5-oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |