Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.60 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.56 |
| ▸ | APLNR | P35414 | 1/20 | 0.56 |
| ▸ | REN | P00797 | 2/20 | 0.55 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.54 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29551271 | 1.00 | C5AR1 (0.62) | C5AR1AGTR2AGTR1EPHA2APLNR | |
| SCHEMBL29976758 | 0.97 | AGTR2 (0.65) | C5AR1AGTR2AGTR1EPHA2APLNR | |
| [Val5] - Angiotensin Ii SCHEMBL29551599 | 0.97 | AGTR2 (0.64) | C5AR1AGTR2AGTR1EPHA2APLNR | |
| SCHEMBL29976469 | 0.95 | C5AR1 (0.65) | C5AR1AGTR2AGTR1EPHA2APLNR | |
| SCHEMBL29619803 | 0.95 | C5AR1 (0.65) | C5AR1AGTR2AGTR1EPHA2APLNR | |
| SCHEMBL29701253 | 0.94 | C5AR1 (0.64) | C5AR1AGTR2AGTR1EPHA2APLNR | |
| SCHEMBL31544391 | 0.94 | AGTR1 (0.62) | C5AR1AGTR2AGTR1APLNRNMUR2 | |
| Angiotensin Ii SCHEMBL9013950 | 0.94 | AGTR2 (0.69) | C5AR1AGTR2AGTR1EPHA2APLNR | |
| Angiotensin Ii SCHEMBL9013957 | 0.94 | AGTR2 (0.69) | C5AR1AGTR2AGTR1EPHA2APLNR | |
| Angiotensin Ii SCHEMBL22125774 | 0.94 | AGTR2 (0.69) | C5AR1AGTR2AGTR1EPHA2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114556100-A | Therapy guidance and/or therapy monitoring for treatment of shock | 4TEEN4制药有限公司 | 2022-05-27 | — | — | CN | disclosed |